Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance
about
Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR NetworkWhat can we learn from fitness landscapes?In Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered GrowthDiversity-oriented synthesis yields novel multistage antimalarial inhibitorsA genomic and evolutionary approach reveals non-genetic drug resistance in malariaMuddled mechanisms: recent progress towards antimalarial target identificationCompounds that select against the tetracycline-resistance efflux pumpMolecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance TransporterA Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug PiperaquineMultidrug evolutionary strategies to reverse antibiotic resistance.Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrtA broad analysis of resistance development in the malaria parasitePlasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes.Collateral sensitivity of antibiotic-resistant microbes.Malaria Genomics in the Era of Eradication.Resisting resistance: is there a solution for malaria?Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic.Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.Determination of the cytostatic and cytocidal activities of antimalarial compounds and their combination interactions.Resource limitation prevents the emergence of drug resistance by intensifying within-host competition.Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum.Antibiotics: New recipe for targeting resistance.Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum.Selection of cytochrome B mutants by putative PfNDH2 inhibitorsMalaria
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P2860
Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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name
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@ast
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@en
type
label
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@ast
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@en
prefLabel
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@ast
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@en
P2093
P2860
P50
P356
P1476
Harnessing evolutionary fitnes ...... ery and suppressing resistance
@en
P2093
Francisco Javier Gamo
Leila Saxby Ross
Maria J Lafuente-Monasterio
Michael L Booker
Richard Heidebrecht
Roger C Wiegand
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P304
P356
10.1073/PNAS.1320886110
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P577
2013-12-31T00:00:00Z