Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus.
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Nuclear Tau and Its Potential Role in Alzheimer's DiseaseTau physiology and pathomechanisms in frontotemporal lobar degenerationAnalyzing dendritic spine pathology in Alzheimer's disease: problems and opportunitiesRoles of tau protein in health and disease.Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model.Tau aggregation and its interplay with amyloid-β.Ectosomes: a new mechanism for non-exosomal secretion of tau protein.Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells.MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy BrainAmyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regionsCo-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease.Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant TauLoss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatinPhysiological and Pathophysiological Implications of Synaptic Tau.Visualizing the microtubule-associated protein tau in the nucleus.Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy.Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies.The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.Atypical, non-standard functions of the microtubule associated Tau protein.Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.Temporally distinct phosphorylations differentiate Tau-dependent learning deficits and premature mortality in Drosophila.Genome instability in Alzheimer disease.A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies.Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy
P2860
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P2860
Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@ast
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@en
type
label
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@ast
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@en
prefLabel
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@ast
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@en
P2860
P1433
P1476
Profiling murine tau with 0N, ...... being enriched in the nucleus.
@en
P2093
P2860
P304
P356
10.1371/JOURNAL.PONE.0084849
P407
P50
P577
2013-12-30T00:00:00Z