Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion.
about
Chemical biology approaches for the study of apicomplexan parasitesIdentification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasionA focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii.Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondiiHow chemoproteomics can enable drug discovery and developmentStreamlining chemical probe discovery: libraries of "fully functionalized" small molecules for phenotypic screening.Target deconvolution techniques in modern phenotypic profiling.Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation.Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion.An in vivo multiplexed small-molecule screening platform.New approaches for dissecting protease functions to improve probe development and drug discoveryA Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells.Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity.High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1.Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis.Screening for small molecule inhibitors of Toxoplasma gondii.Novel drug discovery for Chagas disease.Moving "Forward" in Plasmodium Genetics through a Transposon-Based ApproachGenetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production.Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.Development of an activity-based probe for acyl-protein thioesterases.
P2860
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P2860
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Chemical genetic screen identi ...... ion, attachment, and invasion.
@ast
Chemical genetic screen identi ...... ion, attachment, and invasion.
@en
type
label
Chemical genetic screen identi ...... ion, attachment, and invasion.
@ast
Chemical genetic screen identi ...... ion, attachment, and invasion.
@en
prefLabel
Chemical genetic screen identi ...... ion, attachment, and invasion.
@ast
Chemical genetic screen identi ...... ion, attachment, and invasion.
@en
P2093
P2860
P356
P1476
Chemical genetic screen identi ...... ion, attachment, and invasion.
@en
P2093
Carolyn I Hall
Edgar Deu Sandoval
Eranthie Weerapana
Gary E Ward
Jeralyn D Haraldsen
John C Boothroyd
MacDonald R Phillips
Matthew A Child
Michael L Reese
Paul W Bowyer
P2860
P304
10568-10573
P356
10.1073/PNAS.1105622108
P407
P577
2011-06-13T00:00:00Z