Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
about
Ab initio path-integral calculations of kinetic and equilibrium isotope effects on base-catalyzed RNA transphosphorylation models.QM/MM analysis suggests that Alkaline Phosphatase (AP) and nucleotide pyrophosphatase/phosphodiesterase slightly tighten the transition state for phosphate diester hydrolysis relative to solution: implication for catalytic promiscuity in the AP supeQuantum mechanical modeling: a tool for the understanding of enzyme reactions.Exact Relation between Potential of Mean Force and Free-Energy ProfileAnalysis of proton wires in the enzyme active site suggests a mechanism of c-di-GMP hydrolysis by the EAL domain phosphodiesterases.Comment on "Substrate Folding Modes in Trichodiene Synthase: A Determinant of Chemo- and Stereoselectivity".
P2860
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
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2011 nî lūn-bûn
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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
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2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@ast
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@en
type
label
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@ast
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@en
prefLabel
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@ast
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@en
P2860
P1433
P1476
Insight into the phosphodiesterase mechanism from combined QM/MM free energy simulations.
@en
P2093
Kin-Yiu Wong
P2860
P304
P356
10.1111/J.1742-4658.2011.08187.X
P407
P577
2011-06-14T00:00:00Z