Sequence-specific transcriptional activation is essential for growth suppression by p53.
about
Complex formation of the nonstructural protein 3 of hepatitis C virus with the p53 tumor suppressorei24, a p53 response gene involved in growth suppression and apoptosisp53 regulation of G(2) checkpoint is retinoblastoma protein dependentTwo domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repressionThe MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion proteinp53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damageExpression of the papillomavirus E2 protein in HeLa cells leads to apoptosisAMF1 (GPS2) modulates p53 transactivationp53 Stimulates TFIID-TFIIA-promoter complex assembly, and p53-T antigen complex inhibits TATA binding protein-TATA interactionRepression of RNA polymerase I transcription by the tumor suppressor p53MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MGene regulation by temperature-sensitive p53 mutants: identification of p53 response genesThe first 30 years of p53: growing ever more complexMechanisms of G2 arrest in response to overexpression of p53Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogeneGene therapy for carcinoma of the breast: Therapeutic genetic correction strategiesNovel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2Alterations of the TP53 gene in gastric and esophageal carcinogenesisCrystal structure of a p53 core tetramer bound to DNACrystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstromsWild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor geneIdentification and characterization of the cytoplasmic protein TRAF4 as a p53-regulated proapoptotic genePhysical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53MDM2 and promyelocytic leukemia antagonize each other through their direct interaction with p53BID regulation by p53 contributes to chemosensitivityActivation and activities of the p53 tumour suppressor proteinOligomerization is required for p53 to be efficiently ubiquitinated by MDM2p53 oligomerization and DNA looping are linked with transcriptional activationInteraction of p53 with its consensus DNA-binding siteFactors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain.Function of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.[Retroviral reporter systems for the assessment of activity of stress-induced signal transduction pathways controlled by p53, HIF-1 and HSF-1 transcription factors].Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription.[Transcriptional inhibition of human papilloma virus in cervical carcinoma cells reactivates functions of the tumor suppressor p53].Noncanonical DNA motifs as transactivation targets by wild type and mutant p53p53 binds selectively to the 5' untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4.Insights into cancer from transgenic mouse models.Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrestThe human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.
P2860
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P2860
Sequence-specific transcriptional activation is essential for growth suppression by p53.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@ast
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@en
type
label
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@ast
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@en
prefLabel
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@ast
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@en
P2093
P2860
P50
P356
P1476
Sequence-specific transcriptional activation is essential for growth suppression by p53.
@en
P2093
J A Pietenpol
W S el-Deiry
P2860
P304
P356
10.1073/PNAS.91.6.1998
P407
P577
1994-03-01T00:00:00Z