Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
about
ZBP-89 promotes growth arrest through stabilization of p53Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins.Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer riskLimited importance of the dominant-negative effect of TP53 missense mutationsHigh-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assaysThe role of tetramerization in p53 function.A preclinical study combining the DNA repair inhibitor Dbait with radiotherapy for the treatment of melanoma.Crippling p53 activities via knock-in mutations in mouse models.Likelihood models of somatic mutation and codon substitution in cancer genes.Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53.Ovarian cancer: in search of better marker systems based on DNA repair defectsAggregation tendencies in the p53 family are modulated by backbone hydrogen bonds.Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect.Abnormalities of the p53 Tumour Suppressor Gene in Mature B-cell Neoplasms.Resistance of mitochondrial p53 to dominant inhibition.Inhibition of p53 tumor suppressor by viral interferon regulatory factor.DNA substrate dependence of p53-mediated regulation of double-strand break repair.The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7.Induction of p53-independent apoptosis by the BH3-only protein ITM2Bs.Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants.The murine telomerase catalytic subunit shares the PAb-240 mutant specific epitope of the p53 protein.Flavonoid apigenin inhibits motility and invasiveness of carcinoma cells in vitro.Identification of genomic DNA sequences bound by mutant p53 protein (Gly245-->Ser) in vivo.Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice.
P2860
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P2860
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@ast
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@en
type
label
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@ast
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@en
prefLabel
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@ast
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@en
P2860
P356
P1433
P1476
Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
@en
P2093
P2860
P304
P356
10.1515/BC.1999.108
P577
1999-07-01T00:00:00Z