about
Shortcomings in the current treatment of epilepsyRLIP76, a non-ABC transporter, and drug resistance in epilepsy.Modern antiepileptic drug development has failed to deliver: ways out of the current dilemma.Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy.Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data.Vascular colocalization of P-glycoprotein, multidrug-resistance associated protein 1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies.Drug-Resistant Epilepsy: Multiple Hypotheses, Few AnswersBlood-brain barrier active efflux transporters: ATP-binding cassette gene family.Drug resistance in brain diseases and the role of drug efflux transporters.A new potential AED, carisbamate, substantially reduces spontaneous motor seizures in rats with kainate-induced epilepsyPhenobarbital for the treatment of epilepsy in the 21st century: a critical review.Pharmacogenetics goes genomic.Potential role of drug transporters in the pathogenesis of medically intractable epilepsy.Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms.Characterization of the gene expression profile of human hippocampus in mesial temporal lobe epilepsy with hippocampal sclerosis.The role of common variation in drug transporter genes in refractory epilepsy.Genetics of drug resistance.Refractory epilepsy: mechanisms and solutions.Genetic association studies in epilepsy pharmacogenomics: lessons learnt and potential applications.The progression of epilepsy.Multidrug resistance in epilepsy: a pharmacogenomic update.Imaging of P-glycoprotein function and expression to elucidate mechanisms of pharmacoresistance in epilepsy.Association between ABCB1-T1236C polymorphism and drug-resistant epilepsy in Iranian female patients.Association of SCN1A gene polymorphism with antiepileptic drug responsiveness in the population of Thrace, Greece.Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations.Epilepsy in the cancer patient.Drug resistance in epilepsy and the ABCB1 gene: The clinical perspective.Mechanisms of drug resistance in epilepsy: relevance for antiepileptic drug discovery.Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance.New developments in antiepileptic drug resistance: an integrative viewComparison of brain extracellular fluid, brain tissue, cerebrospinal fluid, and serum concentrations of antiepileptic drugs measured intraoperatively in patients with intractable epilepsy.Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats.Involvement of p38 MAPK in the Drug Resistance of Refractory Epilepsy Through the Regulation Multidrug Resistance-Associated Protein 1.How to explain multidrug resistance in epilepsy?The etiological role of blood-brain barrier dysfunction in seizure disordersABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients.Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy.Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures.Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mechanisms of antiepileptic drug resistance.
@ast
Mechanisms of antiepileptic drug resistance.
@en
type
label
Mechanisms of antiepileptic drug resistance.
@ast
Mechanisms of antiepileptic drug resistance.
@en
prefLabel
Mechanisms of antiepileptic drug resistance.
@ast
Mechanisms of antiepileptic drug resistance.
@en
P1476
Mechanisms of antiepileptic drug resistance.
@en
P2093
Sanjay M Sisodiya
P304
P356
10.1097/00019052-200304000-00013
P577
2003-04-01T00:00:00Z