Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.
about
Regulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsAn integrative modeling framework reveals plasticity of TGF-β signaling.Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.The self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.Dynamics of TGF-β/Smad signalingPlasticity of TGF-β signalingDynamic regulation of Tgf-B signaling by Tif1γ: a computational approach.Burst BMP triggered receptor kinase activity drives Smad1 mediated long-term target gene oscillation in C2C12 cellsThe duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.Characterization of negative feedback network motifs in the TGF-β signaling pathwayLoss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-β and induce Tregs development via TGF-β.Response to Nodal morphogen gradient is determined by the kinetics of target gene induction.Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels.Partners in crime: the TGFβ and MAPK pathways in cancer progression.Non-canonical Activation of Akt in Serum-Stimulated Fibroblasts, Revealed by Comparative Modeling of Pathway DynamicsMathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching.Cellular re- and de-programming by microenvironmental memory: why short TGF-β1 pulses can have long effects.Examining Crosstalk among Transforming Growth Factor β, Bone Morphogenetic Protein, and Wnt PathwaysLiterature-based automated reconstruction, expansion, and refinement of the TGF-β superfamily ligand-receptor network.A comparative review of computational methods for pathway perturbation analysis: dynamical and topological perspectives.Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer.Modelling the molecular mechanisms of aging.Linear-No-Threshold Default Assumptions are Unwarranted for Cytotoxic Endpoints Independently Triggered by Ultrasensitive Molecular Switches.Measuring TGF-β Ligand Dynamics in Culture Medium.PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition.Demystifying the cytokine network: Mathematical models point the way.In silico identification of potential therapeutic targets in the TGF-β signal transduction pathway.Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway.Long-term exposure to bisphenol A or benzo(a)pyrene alters the fate of human mammary epithelial stem cells in response to BMP2 and BMP4, by pre-activating BMP signaling.Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation.Aqueous two-phase printing of cell-containing contractile collagen microgels.Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.Spatiotemporal Control of TGF-β Signaling with Light.Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.TGF-β and IL-6 family signalling crosstalk: an integrated model.Response to comment on "Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway"-Smad2/3 activity does not predict the dynamics of transcription.Comment on "Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway"-Smad2/3 activity does not predict the dynamics of transcription.Pathway crosstalk enables cells to interpret TGF-β duration.
P2860
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P2860
Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Quantitative analysis of trans ...... h factor-β signaling dynamics.
@ast
Quantitative analysis of trans ...... h factor-β signaling dynamics.
@en
type
label
Quantitative analysis of trans ...... h factor-β signaling dynamics.
@ast
Quantitative analysis of trans ...... h factor-β signaling dynamics.
@en
prefLabel
Quantitative analysis of trans ...... h factor-β signaling dynamics.
@ast
Quantitative analysis of trans ...... h factor-β signaling dynamics.
@en
P2093
P2860
P50
P356
P1476
Quantitative analysis of trans ...... th factor-β signaling dynamics
@en
P2093
Aristidis Moustakas
Difan Deng
Edda Klipp
Markus Dahl
Zipei Feng
P2860
P356
10.1038/MSB.2011.22
P577
2011-05-01T00:00:00Z