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High-risk corneal allografts: A therapeutic challengeIFN-γ blocks CD4+CD25+ Tregs and abolishes immune privilege of minor histocompatibility mismatched corneal allografts.Corneal transplantation and immune privilege.New twists to an old story: novel concepts in the pathogenesis of allergic eye disease.IL-17A-dependent CD4+CD25+ regulatory T cells promote immune privilege of corneal allograftsNeutralization of mouse interleukin-17 bioactivity inhibits corneal allograft rejection.IL-17-dependent, IFN-gamma-independent tumor rejection is mediated by cytotoxic T lymphocytes and occurs at extraocular sites, but is excluded from the eye.Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis.In vivo downregulation of innate and adaptive immune responses in corneal allograft rejection by HC-HA/PTX3 complex purified from amniotic membraneSevering corneal nerves in one eye induces sympathetic loss of immune privilege and promotes rejection of future corneal allografts placed in either eye.IFN-γ-independent intraocular tumor rejection is mediated by a macrophage-dependent process that leaves the eye intact.Leptin deficiency modulates allograft survival by favoring a Th2 and a regulatory immune profile. [corrected].Corneal Allograft Rejection: Immunopathogenesis to Therapeutics.CD154 blockade modulates the ratio of Treg to Th1 cells and prolongs the survival of allogeneic corneal grafts in mice.Strategies for local gene therapy of corneal allograft rejection.Immunology of Corneal Allografts: Insights from Animal Models.Alloimmunity and Tolerance in Corneal Transplantation.Anti-IL-17 therapy restricts and reverses late-term corneal allorejection.Paradigm shifts in the role of CD4+ T cells in keratoplastyGamma-irradiation reduces the allogenicity of donor corneas.Role of IFN-γ in the establishment of anterior chamber-associated immune deviation (ACAID)-induced CD8+ T regulatory cells.Therapeutic approaches for induction of tolerance and immune quiescence in corneal allotransplantation.The Effects of Anti-LAP Monoclonal Antibody Down-regulation of CD4+LAP+ T Cells on Allogeneic Corneal Transplantation in Mice.
P2860
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P2860
description
2010 nî lūn-bûn
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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
IL-17 promotes immune privilege of corneal allografts
@ast
IL-17 promotes immune privilege of corneal allografts
@en
type
label
IL-17 promotes immune privilege of corneal allografts
@ast
IL-17 promotes immune privilege of corneal allografts
@en
prefLabel
IL-17 promotes immune privilege of corneal allografts
@ast
IL-17 promotes immune privilege of corneal allografts
@en
P2093
P2860
P356
P1476
IL-17 promotes immune privilege of corneal allografts
@en
P2093
Jerry Y Niederkorn
Khrishen Cunnusamy
Peter W Chen
P2860
P304
P356
10.4049/JIMMUNOL.1001576
P407
P577
2010-09-15T00:00:00Z