Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.
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A gamma interferon independent mechanism of CD4 T cell mediated control of M. tuberculosis infection in vivoTim3 binding to galectin-9 stimulates antimicrobial immunityPhosphoantigen/IL2 expansion and differentiation of Vγ2Vδ2 T cells increase resistance to tuberculosis in nonhuman primatesHow (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transferCD4+ T cells contain early extrapulmonary tuberculosis (TB) dissemination and rapid TB progression and sustain multieffector functions of CD8+ T and CD3- lymphocytes: mechanisms of CD4+ T cell immunity.Immunization of mice with a recombinant adenovirus vaccine inhibits the early growth of Mycobacterium tuberculosis after infectionPolyclonal activation of naïve T cells by urease deficient-recombinant BCG that produced protein complex composed of heat shock protein 70, CysO and major membrane protein-IIDecreased expression of perforin in CD8+ T lymphocytes in patients with Mycobacterium tuberculosis infection and its potential value as a marker for efficacy of treatment.High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protectionDiscovery of novel cross-protective Rickettsia prowazekii T-cell antigens using a combined reverse vaccinology and in vivo screening approachAltered CD8(+) T cell frequency and function in tuberculous lymphadenitis.Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.High efficiency of antiviral CD4(+) killer T cellsBone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatmentImmunostimulatory activity of major membrane protein II from Mycobacterium tuberculosisHuman lung immunity against Mycobacterium tuberculosis: insights into pathogenesis and protection.iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccinationEicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.Impaired degranulation and proliferative capacity of Mycobacterium tuberculosis-specific CD8+ T cells in HIV-infected individuals with latent tuberculosis.Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection.Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR SelectionA Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates.Understanding latent tuberculosis: a moving target.A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during TuberculosisInterleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection.Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques.Prime-boost vaccination with rBCG/rAd35 enhances CD8⁺ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates.Vaccination Produces CD4 T Cells with a Novel CD154-CD40-Dependent Cytolytic MechanismIL-2 simultaneously expands Foxp3+ T regulatory and T effector cells and confers resistance to severe tuberculosis (TB): implicative Treg-T effector cooperation in immunity to TB.CD4+ T cell-dependent IFN-γ production by CD8+ effector T cells in Mycobacterium tuberculosis infectionTim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions.Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse modelMultiple Inflammatory Cytokines Converge To Regulate CD8+ T Cell Expansion and Function during TuberculosisDiscovering naturally processed antigenic determinants that confer protective T cell immunity.HIV-1 and the immune response to TB.An unbiased peptide-wide discovery approach to select Mycobacterium tuberculosis antigens that target CD8+ T cell response during infection.Maintenance of peripheral T cell responses during Mycobacterium tuberculosis infection.Stimulation through CD40 and TLR-4 Is an Effective Host Directed Therapy against Mycobacterium tuberculosis.Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair.
P2860
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P2860
Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@ast
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@en
type
label
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@ast
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@en
prefLabel
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@ast
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@en
P2093
P2860
P1476
Mycobacterium tuberculosis-spe ...... nd provide protection in vivo.
@en
P2093
Joshua S Woodworth
Samuel M Behar
P2860
P304
P356
10.4049/JIMMUNOL.181.12.8595
P407
P577
2008-12-01T00:00:00Z