Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system.
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Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia.Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in ratsDistribution and effects of the muscarinic receptor subtypes in the primary visual cortexNew approaches for the study of orexin function.A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.The antipsychotic potential of muscarinic allosteric modulationM4 muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition.A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairmentMolecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic propertiesLarge-scale in silico mapping of complex quantitative traits in inbred mice.Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists.Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moietiesSynthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen.Synthesis and SAR of N-(4-(4-alklylpiperazin-1-yl)phenyl)benzamides as muscarinic acetylcholine receptor subtype 1 (M1) anatgonists.Allosteric Modulation of Muscarinic Acetylcholine Receptors.Somatodendritic targeting of M5 muscarinic receptor in the rat ventral tegmental area: implications for mesolimbic dopamine transmissionStriatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum.Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons.Functional M3 muscarinic acetylcholine receptors in mammalian heartsMouse Models of Primary Sjogren's Syndrome.Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa.Pharmacological Mechanisms of Cortical Enhancement Induced by the Repetitive Pairing of Visual/Cholinergic Stimulation.Constitutive activity of muscarinic acetylcholine receptors.The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology.Towards a muscarinic hypothesis of schizophrenia.Changes in BQCA Allosteric Modulation of [(3)H]NMS Binding to Human Cortex within Schizophrenia and by Divalent Cations.Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants.Animal models in autoimmune diseases: lessons learned from mouse models for Sjögren's syndrome.Development of M1 mAChR allosteric and bitopic ligands: prospective therapeutics for the treatment of cognitive deficitsQuantitative analysis of the loss of muscarinic receptors in various peripheral tissues in M1-M5 receptor single knockout mice.Preserving cognitive function for patients with overactive bladder: evidence for a differential effect with darifenacin.The muscarinic acetylcholine receptor agonist BuTAC mediates antipsychotic-like effects via the M4 subtypeSpinal muscarinic receptors are activated during low or high frequency TENS-induced antihyperalgesia in rats.Systematic review and meta-analysis: do clinical trials testing antimuscarinic agents for overactive bladder adequately measure central nervous system adverse events?Anticholinergics in palliative medicine: an update.M1 muscarinic acetylcholine receptor in Alzheimer's diseaseNon-neuronal functions of the m2 muscarinic acetylcholine receptor.Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.Microscopic binding of M5 muscarinic acetylcholine receptor with antagonists by homology modeling, molecular docking, and molecular dynamics simulationSynthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor.
P2860
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P2860
Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@ast
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@en
type
label
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@ast
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@en
prefLabel
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@ast
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@en
P2093
P356
P1476
Use of M1-M5 muscarinic recept ...... muscarinic cholinergic system.
@en
P2093
Christian C Felder
David L McKinzie
Frank P Bymaster
Jürgen Wess
P2888
P304
P356
10.1023/A:1022844517200
P577
2003-04-01T00:00:00Z
P6179
1028921874