Interspecies pharmacokinetics and in vitro metabolism of SQ109.
about
Emerging strategies for the treatment of pulmonary tuberculosis: promise and limitations?Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamideIn vitro characterization of the anti-bacterial activity of SQ109 against Helicobacter pyloriInsights into the pharmacokinetic properties of antitubercular drugs.Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action.The chemical biology of new drugs in the development for tuberculosis.Drug-resistant tuberculosis: emerging treatment options.Current development and future prospects in chemotherapy of tuberculosisDose escalation pharmacokinetics and lipid lowering activity of a novel farnesoid X receptor modulator: 16-Dehydropregnenolone.SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.TB and HIV Therapeutics: Pharmacology Research Priorities.New drugs and regimens for treatment of TB.The conduct of drug metabolism studies considered good practice (I): analytical systems and in vivo studiesThe conduct of drug metabolism studies considered good practice (II): in vitro experimentsNew drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections.Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target.New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development.Emerging drugs for the treatment of tuberculosis.Challenges and opportunities in developing novel drugs for TB.Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets.Antituberculosis drug research: a critical overview.Targeting the mycobacterial envelope for tuberculosis drug development.Nontraditional therapies to treat Helicobacter pylori infection.Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients.Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination.In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors.Sex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite).A novel SPE-HPLC method for simultaneous determination of selected sulfonated phthalocyanine zinc complexes in mouse plasma following cassette dosing
P2860
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P2860
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
@ast
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
@en
type
label
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
@ast
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
@en
prefLabel
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
@ast
Interspecies pharmacokinetics and in vitro metabolism of SQ109.
@en
P2093
P2860
P356
P1476
Interspecies pharmacokinetics and in vitro metabolism of SQ109
@en
P2093
Gregory S Gorman
Joseph E Tomaszewski
Lori Coward
Marina Protopopova
Patricia E Noker
P2860
P304
P356
10.1038/SJ.BJP.0706650
P407
P50
P577
2006-03-01T00:00:00Z