Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner

Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner

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http://www.wikidata.org/entity/Q35102100
Roles of protein arginine methyltransferases in the control of glucose metabolismInhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation.Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.New Insights into Orphan Nuclear Receptor SHP in Liver CancerAberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2.Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase.Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genesPRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.Epigenomic regulation of bile acid metabolism: emerging role of transcriptional cofactors.Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.
P2860

Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner

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http://www.wikidata.org/entity/Q35102100
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2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
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2011年論文
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2011年論文
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2011年论文
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Arginine methylation by PRMT5 ...... n by small heterodimer partner
@ast
Arginine methylation by PRMT5 ...... n by small heterodimer partner
@en
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label
Arginine methylation by PRMT5 ...... n by small heterodimer partner
@ast
Arginine methylation by PRMT5 ...... n by small heterodimer partner
@en
prefLabel
Arginine methylation by PRMT5 ...... n by small heterodimer partner
@ast
Arginine methylation by PRMT5 ...... n by small heterodimer partner
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Arginine methylation by PRMT5 ...... n by small heterodimer partner
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932