Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.
about
What do human parasites do with a chloroplast anyway?Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microtiThe metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium sppA sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasitesA systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factorExperimental Genetics of Plasmodium berghei NFU in the Apicoplast Iron-Sulfur Cluster Biogenesis PathwayToxoplasma gondii Toc75 Functions in Import of Stromal but not Peripheral Apicoplast ProteinsNew Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in PlasmodiumFive questions about non-mevalonate isoprenoid biosynthesisYcf93 (Orf105), a small apicoplast-encoded membrane protein in the relict plastid of the malaria parasite Plasmodium falciparum that is conserved in ApicomplexaTranscriptomic analysis reveals evidence for a cryptic plastid in the colpodellid Voromonas pontica, a close relative of chromerids and apicomplexan parasitesPlasmodium falciparum OTU-like cysteine protease (PfOTU) is essential for apicoplast homeostasis and associates with noncanonical role of Atg8A dual-targeted aminoacyl-tRNA synthetase in Plasmodium falciparum charges cytosolic and apicoplast tRNACysMacrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.Toxoplasma gondii development of its replicative niche: in its host cell and beyond.Gibberellin biosynthetic inhibitors make human malaria parasite Plasmodium falciparum cells swell and rupture to death.Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growthToxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatinAntiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.Genetic manipulation of the Toxoplasma gondii genome by fosmid recombineering.The gatekeeper residue and beyond: homologous calcium-dependent protein kinases as drug development targets for veterinarian Apicomplexa parasites.How do antimalarial drugs reach their intracellular targets?Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors of Trypanosoma cruzi and Toxoplasma gondii.Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii.Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.The HU protein is important for apicoplast genome maintenance and inheritance in Toxoplasma gondiiProtein sorting in complex plastids.Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.Chemobiosynthesis of new antimalarial macrolides.Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.Defining the timing of action of antimalarial drugs against Plasmodium falciparum.Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase.Divergent Isoprenoid Biosynthesis Pathways in Staphylococcus Species Constitute a Drug Target for Treating Infections in Companion AnimalsDesign, synthesis and biological evaluation of WC-9 analogs as antiparasitic agentsMechanistic aspects of carotenoid biosynthesis.In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan ParasitesMitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii.Targeting apicoplasts in malaria parasites.Isoprenoid biosynthesis in Plasmodium falciparum.
P2860
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P2860
Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Apicoplast isoprenoid precurso ...... sistance in Toxoplasma gondii.
@ast
Apicoplast isoprenoid precurso ...... sistance in Toxoplasma gondii.
@en
type
label
Apicoplast isoprenoid precurso ...... sistance in Toxoplasma gondii.
@ast
Apicoplast isoprenoid precurso ...... sistance in Toxoplasma gondii.
@en
prefLabel
Apicoplast isoprenoid precurso ...... sistance in Toxoplasma gondii.
@ast
Apicoplast isoprenoid precurso ...... sistance in Toxoplasma gondii.
@en
P2093
P2860
P50
P921
P356
P1476
Apicoplast isoprenoid precurso ...... esistance in Toxoplasma gondii
@en
P2093
Angelika Sturm
Carrie F Brooks
Justin L Anglin
Sethu C Nair
Silvia N J Moreno
Yongcheng Song
P2860
P304
P356
10.1084/JEM.20110039
P407
P577
2011-06-20T00:00:00Z