Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease - Wikidata - wikimedia - TriplyDB

Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease

Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease

http://www.wikidata.org/entity/Q35103074

about

Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain Calpastatin modulates APP processing in the brains of β-amyloid depositing but not wild-type mice Expression of calpain-calpastatin system (CCS) member proteins in human lymphocytes of young and elderly individuals; pilot baseline data for the CALPACENT project.Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression.The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models.Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments.Implicating calpain in tau-mediated toxicity in vivo.The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration.Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression.Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms.Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease.Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects.Calpain dysregulation in Alzheimer's disease Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE.A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes β-Amyloid carrying the Dutch mutation has diverse effects on calpain-mediated toxicity in hippocampal neurons.Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons.Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease.Proteolytic mechanisms in necrotic cell death and neurodegeneration.Neurofilaments at a glance.Implication of calpain in neuronal apoptosis. A possible regulation of Alzheimer's disease.Involvement of calpain activation in neurodegenerative processes.CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease.Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.Semiquantitative proteomic analysis of human hippocampal tissues from Alzheimer's disease and age-matched control brains.Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons Cardiac dys-synchronization and arrhythmia in hyperhomocysteinemia.Neurites containing the neurofilament-triplet proteins are selectively vulnerable to cytoskeletal pathology in Alzheimer's disease and transgenic mouse models.Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production.PSEA: Kinase-specific prediction and analysis of human phosphorylation substrates.Axonal degeneration as a therapeutic target in the CNS.Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors.Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.Calpain-14 and its association with eosinophilic esophagitis.

P2860

Q27693256-798AB3D7-1F6D-4FF8-BB57-11FBE79D658A Q27865198-6512350D-ECCE-45CB-A0CF-2C28FC20B333 Q30454134-FD79ED46-0826-4F4B-B5BE-F8D6BD610C87 Q30654017-92454400-6B07-4BD6-BDA3-CC67C3B92AFE Q33640651-622977BD-8B5A-4222-BDAB-1E71A58B34FA Q33823446-632C2BAE-99BC-42AE-9D54-8E7D9766AECB Q33865294-339C53FC-40B7-4DC9-87ED-86F6803A4DBE Q33937493-FE87FA86-9E32-44FB-8160-64D608072655 Q34000095-D87E317F-447E-4994-B298-F5BB3E0D6921 Q34316318-1967C5E0-EF7C-469B-866E-54C0A441F880 Q34410183-3D76182C-4B5B-445F-8FD5-4D162C320691 Q34493905-C11FDB0C-9C26-4864-8FAB-B224EE533499 Q34579467-C36A007C-5421-47D3-A0F1-D211422240AC Q35035648-B6D9E5F2-EA3B-4007-82D2-0EBCE6DA0355 Q35059268-1329C6EE-84F8-4CBA-ADE4-4A3A957EF76A Q35361462-C51DA8FA-6011-4ADB-99C2-67506B6BCF9E Q35721878-F5805A84-BF3A-4E22-A513-3C2926F6600C Q35766384-6EBE2A89-D940-4DFF-977B-B1CDBCCD1E37 Q35794263-19C44F23-C5C5-4A14-9BB6-C82300F556B9 Q35872520-A5CD42CE-ABCF-4E53-B798-1A94E77D9519 Q35955892-50FA53B0-F290-4190-9A1F-6897165C6F20 Q36039037-1035DC15-E7EE-447E-B832-042AC8102C82 Q36156010-4850B064-7E5D-49EF-8B97-B6D680AA4EE3 Q36450980-3E7E21C5-A5C4-4A41-BD12-5F2E66A0E33C Q36554860-A6D14030-117D-4375-A06C-8BD84CAF14C7 Q36588397-42A5D01D-246C-4107-9E64-C48966BBC84F Q36684722-527B90E8-3A68-4A15-AE38-42022983B355 Q36740290-1B3262FB-F98E-4C21-B6A3-C59B225B6669 Q36758446-4402EE45-206C-48A1-961C-5CA9D6CF79EF Q36828165-899315FD-15FC-4FE1-AB6B-1F89AE1E5FAE Q36978473-65D1CA00-B77E-4D67-B69E-33DAF664117A Q37017926-67260197-3DEC-4EC1-A86A-98EEB1BA862B Q37199238-6B6846D3-7848-40EB-8CA1-D32B0441F09B Q37237452-0922C39A-F2C7-4ED3-AE99-E7CE3ED752DF Q37610928-D3679A8E-25C5-45B3-8669-58CF7ACD6904 Q37673104-80C8A5A6-9FAC-4D9D-BDFE-E629CA25E633 Q37990880-0AEF9AAD-9319-48BC-BAD0-D855D721667C Q38409713-A3B0C6F5-F155-4D7D-A25F-1073DE6B4815 Q38659874-27AE7BF8-01DC-46FD-9AB8-6EFA88527B54 Q39107690-420CD3CF-2E4F-46D2-8007-4ED53D5BE673

P2860

Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease

http://www.wikidata.org/entity/Q35103074

description

2004 nî lūn-bûn

@nan

2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@ast

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@en

type

label

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@ast

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@en

prefLabel

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@ast

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@en

P1433

Q35103074-7AB4E4D2-E9A7-41F9-B05D-A93798DC3C5A

P1476

Q35103074-F0811E01-36ED-4497-B036-0DF8DB9094D2

P2093

Q35103074-0C2903DA-78EF-4EA6-97B9-BECA1B53F95A

Q35103074-1CD2FCF1-5B35-4675-84B6-F7D3B0D51CE1

Q35103074-1F50D9C3-51A6-400E-B467-70E6472AE3A0

Q35103074-36B0FB3D-5FAE-46E0-B3E2-16778EA6C07E

Q35103074-400761A2-0F0C-4CA7-9D1D-796768BCBF66

Q35103074-44D33F85-EF79-481E-A33D-7C8C26AEF7A9

Q35103074-616E02E5-0924-45C8-9A00-178EADB11491

Q35103074-82D795D3-74A8-4795-952F-C801ED7A0335

Q35103074-9248EC69-B8AF-40E7-AB22-151BF39C91EC

Q35103074-93B9359A-A8D6-40E3-A7A6-81D767EB0CB6

P2860

Q35103074-038670BD-4BC8-4CB5-8762-796013FEB110

Q35103074-05C9F7A7-4559-4ED6-AE61-23DA2603A7AA

Q35103074-0782AF8D-DF5C-40F6-89EF-A810700DD4B1

Q35103074-0A6B5629-21EF-47E3-B1A9-E012C4659A87

Q35103074-0D96FD78-0AC1-4592-8C0B-F2591B63D236

Q35103074-15A0489E-2EED-4C5E-8F44-CB198082074A

Q35103074-17B809FC-5DBC-4C02-841D-856EBE2530F3

Q35103074-19DFD5E8-448C-43E7-BDB8-7373CB8E9A17

Q35103074-1BE94772-466B-445C-8276-F0CB7E802593

Q35103074-2321B4F4-5586-4D60-B389-A403C36C518D

P304

Q35103074-C94FB4E6-B5D2-4126-B6F2-08BD1A15F89C

P31

Q35103074-FADC2963-F055-43B4-9A6B-2CA7F6D3D0D8

P356

Q35103074-14CF6B19-A618-4CF5-9B51-5137C13563AF

P407

Q35103074-AD12C48B-BD22-4402-9466-A0E3DED32487

P433

Q35103074-F1E6E9C2-EEE7-45D7-83A1-DFF6EF13DBAD

P478

Q35103074-B189C691-7FDE-435F-A6B5-FEC5E295381E

P50

Q35103074-99C512C4-B31C-4748-A6B7-2479A2E6F6B5

Q35103074-DDFA7D20-6548-4B60-9BA9-372DCA7F3A4C

P577

Q35103074-F381951A-0CED-4A00-A470-C882C2D65837

P698

Q35103074-BA5054F0-CDFE-45E2-9F86-1EC266047B37

P921

Q35103074-2E4355EB-24B2-431E-A885-292BD6C90858

Q35103074-75AA94EB-2F36-499A-911E-5D8246780F15

Q35103074-8619F173-FC84-4EA3-BE5F-980134E331CC

P932

Q35103074-21E34015-0B53-4F96-8F94-920F921232DA

P356

S0002-9440(10)63342-1

P1433

The American Journal of Pathology

P1476

Calpain mediates calcium-induc ...... levance to Alzheimer's disease

@en

P2093

Anna Rudnicki

http://www.w3.org/2001/XMLSchema#string

Anne Cataldo

http://www.w3.org/2001/XMLSchema#string

Barry Boland

http://www.w3.org/2001/XMLSchema#string

Basalingappa L Hungund

http://www.w3.org/2001/XMLSchema#string

Bing Sheng Li

http://www.w3.org/2001/XMLSchema#string

Corrinne Peterhoff

http://www.w3.org/2001/XMLSchema#string

Harish C Pant

http://www.w3.org/2001/XMLSchema#string

Niranjana Amin

http://www.w3.org/2001/XMLSchema#string

Panaiyur Mohan

http://www.w3.org/2001/XMLSchema#string

Ralph A Nixon

http://www.w3.org/2001/XMLSchema#string

P2860

The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family

Identification of the major multiphosphorylation site in mammalian neurofilaments

A Ca(2+) switch aligns the active site of calpain

Neuropathological stageing of Alzheimer-related changes

Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: its role in zinc-induced neuronal death

Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Mitogen-activated protein kinase pathways

Crucial role of calpain in hypoxic PC12 cell death: calpain, but not caspases, mediates degradation of cytoskeletal proteins and protein kinase C-alpha and -delta.

P304

795-805

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/S0002-9440(10)63342-1

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

165

http://www.w3.org/2001/XMLSchema#string

P50

Balapal S Basavarajappa

Ottavio Arancio

P577

2004-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15331404

http://www.w3.org/2001/XMLSchema#string

P921

Alzheimer's disease

phosphorylation

P932

1618589

http://www.w3.org/2001/XMLSchema#string