Beneficial effects of ethyl pyruvate through inhibiting high-mobility group box 1 expression and TLR4/NF-κB pathway after traumatic brain injury in the rat.
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Mechanisms and potential therapeutic applications of microglial activation after brain injuryEthyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuriesEmerging therapies in traumatic brain injuryAmyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's diseaseEthyl pyruvate protects against blood-brain barrier damage and improves long-term neurological outcomes in a rat model of traumatic brain injuryEthyl pyruvate inhibits HMGB1 phosphorylation and release by chelating calciumGlucose administration after traumatic brain injury exerts some benefits and no adverse effects on behavioral and histological outcomes.Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro.High-mobility group box 1 induces calcineurin-mediated cell hypertrophy in neonatal rat ventricular myocytesThe toll of the gridiron: damage-associated molecular patterns and hypertension in American football.Persistent adaptation by chronic alcohol is facilitated by neuroimmune activation linked to stress and CRFSignaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.Pyruvate treatment attenuates cerebral metabolic depression and neuronal loss after experimental traumatic brain injuryGlucocorticoids Mediate Short-Term High-Fat Diet Induction of Neuroinflammatory Priming, the NLRP3 Inflammasome, and the Danger Signal HMGB1The cytokine mRNA increase induced by withdrawal from chronic ethanol in the sterile environment of brain is mediated by CRF and HMGB1 release.Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.Anti-inflammatory and anti-excitoxic effects of diethyl oxopropanamide, an ethyl pyruvate bioisoster, exert robust neuroprotective effects in the postischemic brain.Treatment of traumatic brain injury with anti-inflammatory drugs.The danger zone: Systematic review of the role of HMGB1 danger signalling in traumatic brain injury.Sterile Neuroinflammation and Strategies for Therapeutic InterventionWhite matter damage after traumatic brain injury: A role for damage associated molecular patterns.Blood neuron-derived exosomes as biomarkers of cognitive impairment in HIV.Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury.Bone Fracture Enhances Trauma Brain Injury.Anti-inflammatory effects of four potential anti-endotoxaemic drugs assessed in vitro using equine whole blood assays.Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats.Glycyrrhizin attenuates Toll like receptor-2, -4 and experimental vasospasm in a rat model.Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner.Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Post-Natal Day 17 Rats.Ethyl pyruvate does not require microglia for mediating neuroprotection after excitotoxic injury.HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction
P2860
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P2860
Beneficial effects of ethyl pyruvate through inhibiting high-mobility group box 1 expression and TLR4/NF-κB pathway after traumatic brain injury in the rat.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@ast
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@en
type
label
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@ast
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@en
prefLabel
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@ast
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@en
P2093
P2860
P921
P356
P1476
Beneficial effects of ethyl py ...... matic brain injury in the rat.
@en
P2093
P2860
P304
P356
10.1155/2011/807142
P577
2011-06-16T00:00:00Z