Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.
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Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospectsDementia of the eye: the role of amyloid beta in retinal degenerationThe unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein foldingThe proteomics of drusenAt the interface of sensory and motor dysfunctions and Alzheimer's disease.Animal models of age related macular degenerationBeta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD)Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse modelProtection of retina by αB crystallin in sodium iodate induced retinal degenerationOcular indicators of Alzheimer's: exploring disease in the retinaRecent developments in the management of dry age-related macular degenerationAmyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degenerationCoaxial Electrospray of Ranibizumab-Loaded Microparticles for Sustained Release of Anti-VEGF TherapiesMethodologies for analysis of patterning in the mouse RPE sheet.Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats.Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMPThe complexities underlying age-related macular degeneration: could amyloid beta play an important role?Functional principal component analysis reveals discriminating categories of retinal pigment epithelial morphology in mice.Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degenerationQuantitative autofluorescence and cell density maps of the human retinal pigment epithelium.Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease.Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.Update on current and future novel therapies for dry age-related macular degeneration.Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration.Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.Iron increases APP translation and amyloid-beta production in the retina.Interaction of complement factor h and fibulin3 in age-related macular degenerationLipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration.Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cellsA chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in miceRegulation of age-related macular degeneration-like pathology by complement factor H.Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD)Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic miceMulti-nucleate retinal pigment epithelium cells of the human macula exhibit a characteristic and highly specific distribution.Semi-automated discrimination of retinal pigmented epithelial cells in two-photon fluorescence images of mouse retinasGenetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics.Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium.Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysinNovel roles for α-crystallins in retinal function and disease.Dry age-related macular degeneration like pathology in aged 5XFAD mice: Ultrastructure and microarray analysis.
P2860
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P2860
Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Anti-amyloid therapy protects ...... -related macular degeneration.
@ast
Anti-amyloid therapy protects ...... -related macular degeneration.
@en
type
label
Anti-amyloid therapy protects ...... -related macular degeneration.
@ast
Anti-amyloid therapy protects ...... -related macular degeneration.
@en
prefLabel
Anti-amyloid therapy protects ...... -related macular degeneration.
@ast
Anti-amyloid therapy protects ...... -related macular degeneration.
@en
P2093
P2860
P356
P1476
Anti-amyloid therapy protects ...... e-related macular degeneration
@en
P2093
Bing Kuang
Brian E Mace
Catherine Bowes Rickman
Dione Kobayashi
Jaume Pons
Jeanette Dilley
Jeffrey A Jamison
John C Lin
Lincoln V Johnson
Marybeth Groelle
P2860
P304
P356
10.1073/PNAS.1100901108
P407
P577
2011-06-20T00:00:00Z