Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. - Wikidata - wikimedia - TriplyDB

Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.

Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.

http://www.wikidata.org/entity/Q35105102

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Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospects Dementia of the eye: the role of amyloid beta in retinal degeneration The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding The proteomics of drusen At the interface of sensory and motor dysfunctions and Alzheimer's disease.Animal models of age related macular degeneration Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD)Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model Protection of retina by αB crystallin in sodium iodate induced retinal degeneration Ocular indicators of Alzheimer's: exploring disease in the retina Recent developments in the management of dry age-related macular degeneration Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration Coaxial Electrospray of Ranibizumab-Loaded Microparticles for Sustained Release of Anti-VEGF Therapies Methodologies for analysis of patterning in the mouse RPE sheet.Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats.Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP The complexities underlying age-related macular degeneration: could amyloid beta play an important role?Functional principal component analysis reveals discriminating categories of retinal pigment epithelial morphology in mice.Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration Quantitative autofluorescence and cell density maps of the human retinal pigment epithelium.Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease.Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.Update on current and future novel therapies for dry age-related macular degeneration.Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration.Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.Iron increases APP translation and amyloid-beta production in the retina.Interaction of complement factor h and fibulin3 in age-related macular degeneration Lipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration.Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice Regulation of age-related macular degeneration-like pathology by complement factor H.Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD)Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice Multi-nucleate retinal pigment epithelium cells of the human macula exhibit a characteristic and highly specific distribution.Semi-automated discrimination of retinal pigmented epithelial cells in two-photon fluorescence images of mouse retinas Genetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics.Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium.Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin Novel roles for α-crystallins in retinal function and disease.Dry age-related macular degeneration like pathology in aged 5XFAD mice: Ultrastructure and microarray analysis.

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Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.

http://www.wikidata.org/entity/Q35105102

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P2860

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

The potential role of amyloid beta in the pathogenesis of age-related macular degeneration.

Complement factor H polymorphism in age-related macular degeneration

A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

Complement factor H variant increases the risk of age-related macular degeneration

HTRA1 promoter polymorphism in wet age-related macular degeneration

Missense variations in the fibulin 5 gene and age-related macular degeneration

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