Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines.
about
Acid-sensing ion channels in pain and disease.Restrictive expression of acid-sensing ion channel 5 (asic5) in unipolar brush cells of the vestibulocerebellumTwo aspects of ASIC function: Synaptic plasticity and neuronal injury.Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout miceASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis.Physiological and pathological functions of acid-sensing ion channels in the central nervous system.Acid-sensing ion channels: A new target for pain and CNS diseasesExpressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioningProtons act as a transmitter for muscle contraction in C. elegans.Restoring Acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses.Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.Acid-sensing ion channels in mouse olfactory bulb M/T neurons.ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversionASIC2 subunits facilitate expression at the cell surface and confer regulation by PSD-95.The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala.Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking.Transient acidosis while retrieving a fear-related memory enhances its lability.Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cellsMitochondrial fragmentation leads to intracellular acidification in Caenorhabditis elegans and mammalian cells.Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity.The interaction between the first transmembrane domain and the thumb of ASIC1a is critical for its N-glycosylation and trafficking.Acidosis, acid-sensing ion channels, and neuronal cell death.Acid-sensing ion channels: trafficking and synaptic function.Acid sensing ion channel 1 in lateral hypothalamus contributes to breathing controlIdentification of a calcium permeable human acid-sensing ion channel 1 transcript variant.PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner.Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosisRegulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal deathExpression and activity of acid-sensing ion channels in the mouse anterior pituitary.ASIC1A in the bed nucleus of the stria terminalis mediates TMT-evoked freezing.N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling.Cysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition.Calcium-permeable ion channels involved in glutamate receptor-independent ischemic brain injuryInhibition of human acid-sensing ion channel 1b by zincNMDAR-Mediated Hippocampal Neuronal Death is Exacerbated by Activities of ASIC1a.ASIC subunit ratio and differential surface trafficking in the brain.Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms
P2860
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P2860
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Acid-sensing ion channel 1a is ...... e density of dendritic spines.
@ast
Acid-sensing ion channel 1a is ...... e density of dendritic spines.
@en
type
label
Acid-sensing ion channel 1a is ...... e density of dendritic spines.
@ast
Acid-sensing ion channel 1a is ...... e density of dendritic spines.
@en
prefLabel
Acid-sensing ion channel 1a is ...... e density of dendritic spines.
@ast
Acid-sensing ion channel 1a is ...... e density of dendritic spines.
@en
P2093
P2860
P356
P1476
Acid-sensing ion channel 1a is ...... he density of dendritic spines
@en
P2093
Michael J Welsh
Steven H Green
Xiang-ming Zha
P2860
P304
16556-16561
P356
10.1073/PNAS.0608018103
P407
P577
2006-10-23T00:00:00Z