Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir
about
Human cytomegalovirus resistance to antiviral drugsHow I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipientsAntiviral drug resistance in human cytomegalovirusAntiviral properties of a series of 1,6-naphthyridine and 7, 8-dihydroisoquinoline derivatives exhibiting potent activity against human cytomegalovirusAntiviral drug resistance of human cytomegalovirus.Resistance of human cytomegalovirus to antiviral drugs.Clinical uses of cidofovir.Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.A standardized plaque reduction assay for determination of drug susceptibilities of cytomegalovirus clinical isolates.Emergence of multiple human cytomegalovirus ganciclovir-resistant mutants with deletions and substitutions within the UL97 gene in a patient with severe combined immunodeficiency.Detection of human cytomegalovirus mutations associated with ganciclovir resistance in cerebrospinal fluid of AIDS patients with central nervous system disease.Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates.Crystal Structure of the Human Cytomegalovirus Glycoprotein B.The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines.Cytomegalovirus UL97 mutations in the era of ganciclovir and maribavir.The genetic basis of human cytomegalovirus resistance and current trends in antiviral resistance analysis.Antiviral Drug- and Multidrug Resistance in Cytomegalovirus Infected SCT Patients.A nine-codon deletion mutation in the cytomegalovirus UL97 phosphotransferase gene confers resistance to ganciclovir.Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing.Lack of emergence of cytomegalovirus UL97 mutations conferring ganciclovir (GCV) resistance following preemptive GCV therapy in allogeneic stem cell transplant recipients.The Cys607-->Tyr change in the UL97 phosphotransferase confers ganciclovir resistance to two human cytomegalovirus strains recovered from two immunocompromised patients.Human herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovirA recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency.Amino acids of conserved kinase motifs of cytomegalovirus protein UL97 are essential for autophosphorylation.Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action.Assessment of the Human Cytomegalovirus UL97 Gene for Identification of Resistance to Ganciclovir in Iranian Immunosuppressed PatientsRapid simultaneous detection by real-time PCR of cytomegalovirus UL97 mutations in codons 460 and 520 conferring ganciclovir resistance.Detection of Two Drug-Resistance Mutants of the Cytomegalovirus by High-Resolution Melting Analysis.The time course of development and impact from viral resistance against ganciclovir in cytomegalovirus infection.Sequence analysis of UL54 and UL97 genes and evaluation of antiviral susceptibility of human cytomegalovirus isolates obtained from kidney allograft recipients before and after treatment.Cytomegalovirus UL97 and glycoprotein B (gB) sequences in tissues from immunocompromised patients with ganciclovir-resistant virus infection.Genotyping cytomegalovirus UL97 mutations by high-resolution melting analysis with unlabeled probe.
P2860
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P2860
Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@ast
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@en
type
label
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@ast
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@en
prefLabel
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@ast
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@en
P2093
P2860
P356
P1476
Novel mutation in the UL97 gen ...... ring resistance to ganciclovir
@en
P2093
P2860
P304
P356
10.1128/AAC.39.5.1204
P407
P577
1995-05-01T00:00:00Z