Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.
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Human cytomegalovirus resistance to antiviral drugsHow I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipientsEffect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongationAntiviral drug resistance of human cytomegalovirus.Resistance of human cytomegalovirus to antiviral drugs.Recombinant phenotyping of cytomegalovirus UL97 kinase sequence variants for ganciclovir resistance.Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.Heparanase is a host enzyme required for herpes simplex virus-1 release from cells.Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovirDetection of human cytomegalovirus mutations associated with ganciclovir resistance in cerebrospinal fluid of AIDS patients with central nervous system disease.Rhesus cytomegalovirus is similar to human cytomegalovirus in susceptibility to benzimidazole nucleosidesLobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymeraseThe use of antiviral drugs during the neonatal periodThe human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines.Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing.The U69 gene of human herpesvirus 6 encodes a protein kinase which can confer ganciclovir sensitivity to baculoviruses.The Cys607-->Tyr change in the UL97 phosphotransferase confers ganciclovir resistance to two human cytomegalovirus strains recovered from two immunocompromised patients.Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragmentsA recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency.Amino acids of conserved kinase motifs of cytomegalovirus protein UL97 are essential for autophosphorylation.Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovThe UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase.Human cytomegalovirus UL97 kinase confers ganciclovir susceptibility to recombinant vaccinia virus.New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure
P2860
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P2860
Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Mutation in the UL97 open read ...... ains resistant to ganciclovir.
@en
type
label
Mutation in the UL97 open read ...... ains resistant to ganciclovir.
@en
prefLabel
Mutation in the UL97 open read ...... ains resistant to ganciclovir.
@en
P2093
P2860
P1433
P1476
Mutation in the UL97 open read ...... rains resistant to ganciclovir
@en
P2093
Spafford LE
Thompson KD
P2860
P304
P407
P577
1994-07-01T00:00:00Z