Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo.
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Signaling and regulation of G protein-coupled receptors in airway smooth muscleIloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungsChronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha)Can the anti-inflammatory activities of β2-agonists be harnessed in the clinical setting?Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinasesDesensitization of beta2-adrenoceptor-mediated responses by short-acting beta2-adrenoceptor agonists in human lung mast cells.The human near-term myometrial beta 3-adrenoceptor but not the beta 2-adrenoceptor is resistant to desensitisation after sustained agonist stimulation.Regulators of G protein signalling: potential targets for treatment of allergic inflammatory diseases such as asthma.Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma.Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.Pharmacogenomics of beta2-agonist: key focus on signaling pathways.Regulation of heterotrimeric G protein signaling in airway smooth muscle.Construction of a cell model of β2-adrenoceptor downregulation.Differential expression of Gs in a murine model of homocysteinemic heart failureExploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscleNew perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.RGS5 gene and therapeutic response to short acting bronchodilators in paediatric asthma patients.Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscleClenbuterol prevents epinephrine from antagonizing insulin-stimulated muscle glucose uptake.Prolonged isoproterenol infusion impairs the ability of beta(2)-agonists to increase alveolar liquid clearance.Selected contribution: long-term effects of beta(2)-adrenergic receptor stimulation on alveolar fluid clearance in mice.Increased renal angiotensin II AT1 receptor function in obese Zucker rat.Postreceptor defects in alveolar epithelial beta-adrenergic signaling after prolonged isoproterenol infusion.Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase.PKA delivery to the distal lung air spaces increases alveolar liquid clearance after isoproterenol-induced alveolar epithelial PKA desensitization.Upregulation of phosphodiesterase-4 in the lung of allergic rats.A Controlled Trial of Inhaled Bronchodilators in Familial Dysautonomia.Signaling and regulation of G protein-coupled receptors in airway smooth muscle
P2860
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P2860
Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@ast
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@en
type
label
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@ast
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@en
prefLabel
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@ast
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@en
P2093
P2860
P356
P1476
Albuterol-induced downregulati ...... eptor desensitization in vivo.
@en
P2093
Belvisi MG
Donnelly LE
Giembycz MA
P2860
P304
P356
10.1172/JCI8374
P407
P577
2000-07-01T00:00:00Z