Regulation of heterotrimeric G protein signaling in airway smooth muscle.
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A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulationA fungal protease allergen provokes airway hyper-responsiveness in asthma.Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups.Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation.Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe AsthmaKv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy.Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.Regulation of G-protein-coupled signaling pathways in allergic inflammation.Glucocorticoid- and protein kinase A-dependent transcriptome regulation in airway smooth muscle.The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle.KCNQ (Kv7) potassium channel activators as bronchodilators: combination with a β2-adrenergic agonist enhances relaxation of rat airways.β2-Adrenoceptor agonists in the regulation of mitochondrial biogenesis.New perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.cAMP regulation of airway smooth muscle function.Modulation of the cAMP response by Gαi and Gβγ: a computational study of G protein signaling in immune cells.Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the beta2-adrenergic receptor.PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.RGS4 Overexpression in Lung Attenuates Airway Hyper-responsiveness in Mice.Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor.Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner.Regulators of G-Protein Signaling as Asthma Therapy?PDE8 is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2AR-AC6.Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma.PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells.A bronchoprotective role for in a murine model of lipopolysaccharide-induced airways inflammation
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P2860
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@en
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@nl
type
label
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@en
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@nl
prefLabel
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@en
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@nl
P2860
P921
P1476
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
@en
P2093
Jeffrey L Benovic
Raymond B Penn
P2860
P356
10.1513/PATS.200705-054VS
P577
2008-01-01T00:00:00Z