Suppression of systemic autoimmunity by the innate immune adaptor STING. - Wikidata - wikimedia - TriplyDB

Suppression of systemic autoimmunity by the innate immune adaptor STING.

Suppression of systemic autoimmunity by the innate immune adaptor STING.

http://www.wikidata.org/entity/Q35128992

about

Nucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation Apoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunity Pathways leading to an immunological disease: systemic lupus erythematosus.Lupus and proliferative nephritis are PAD4 independent in murine models.USP13 negatively regulates antiviral responses by deubiquitinating STING A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherin IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance STING Negatively Regulates Double-Stranded DNA-Activated JAK1-STAT1 Signaling via SHP-1/2 in B Cells.Animal Models of Interferon Signature Positive Lupus.The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model.What is damaging the kidney in lupus nephritis?Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus.STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology.The role of cGAS in innate immunity and beyond.The expanding regulatory network of STING-mediated signaling.Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?Absent in Melanoma 2 proteins in SLE.The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele.The many ways tissue phagocytes respond to dying cells.Immune Diseases Associated with TREX1 and STING Dysfunction.Regulating STING in health and disease Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signaling complexes.Herpesvirus-Associated Lymphadenitis Distorts Fibroblastic Reticular Cell Microarchitecture and Attenuates CD8 T Cell Responses to Neurotropic Infection in Mice Lacking the STING-IFNα/β Defense Pathways.Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers.Self-dsDNA in the pathogenesis of systemic lupus erythematosus.Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.STING-associated vasculopathy develops independently of IRF3 in mice.iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing.Immunosuppressive CD11b+Ly6Chi monocytes in pristane-induced lupus mouse model.Stimulator of Interferon Genes Promotes Host Resistance Against Pseudomonas aeruginosa Keratitis.

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Suppression of systemic autoimmunity by the innate immune adaptor STING.

http://www.wikidata.org/entity/Q35128992

description

2015 nî lūn-bûn

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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2015 թվականի փետրվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Suppression of systemic autoimmunity by the innate immune adaptor STING.

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Suppression of systemic autoimmunity by the innate immune adaptor STING.

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Suppression of systemic autoimmunity by the innate immune adaptor STING.

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Suppression of systemic autoimmunity by the innate immune adaptor STING.

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Suppression of systemic autoimmunity by the innate immune adaptor STING.

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Suppression of systemic autoimmunity by the innate immune adaptor STING.

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PNAS.1420217112

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Proceedings of the National Academy of Sciences of the United States of America

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Suppression of systemic autoimmunity by the innate immune adaptor STING

@en

P2093

Allison M Campbell

http://www.w3.org/2001/XMLSchema#string

Ann Marshak-Rothstein

http://www.w3.org/2001/XMLSchema#string

Annie H Huyler

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Chandra Mohan

http://www.w3.org/2001/XMLSchema#string

Gregory M Orlowski

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Jennie Chan

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Katherine A Fitzgerald

http://www.w3.org/2001/XMLSchema#string

Kerstin Nündel

http://www.w3.org/2001/XMLSchema#string

Leslie J Berg

http://www.w3.org/2001/XMLSchema#string

Mark J Shlomchik

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P2860

IFI16 is an innate immune sensor for intracellular DNA

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

Trex1 prevents cell-intrinsic initiation of autoimmunity

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

Monocyte recruitment during infection and inflammation

TLRs and IFNs: critical pieces of the autoimmunity puzzle

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E710-7

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10.1073/PNAS.1420217112

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7

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112

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Stefan A Schattgen

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2015-02-02T00:00:00Z

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272429073

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25646421

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4343138

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