Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. - Wikidata - wikimedia - TriplyDB

Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

http://www.wikidata.org/entity/Q35134867

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Inherited platelet disorders: toward DNA-based diagnosis Specification and function of hemogenic endothelium during embryogenesis From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications Epigenetic mechanisms and developmental choice hierarchies in T-lymphocyte development Transcription factors in late megakaryopoiesis and related platelet disorders Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome Cistrome plasticity and mechanisms of cistrome reprogramming The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression The European Hematology Association Roadmap for European Hematology Research: a consensus document Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.Large-scale quality analysis of published ChIP-seq data.Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome.Inherited thrombocytopenias: an approach to diagnosis and management.Novel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish models Pathogenesis and management of inherited thrombocytopenias: rationale for the use of thrombopoietin-receptor agonists.Enrichment of FLI1 and RUNX1 mutations in families with excessive bleeding and platelet dense granule secretion defects.Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation Molecular basis of inherited thrombocytopenias.Hematopoietic transcription factor mutations and inherited platelet dysfunction.NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes Inherited platelet dysfunction and hematopoietic transcription factor mutations.Dawning of the age of genomics for platelet granule disorders: improving insight, diagnosis and management.The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer.Hematopoietic transcription factor mutations: important players in inherited platelet defects.FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology.Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors.Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events.Novel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation.SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume.An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits.Absence of a simple code: how transcription factors read the genome

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Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

http://www.wikidata.org/entity/Q35134867

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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Genome-wide analysis of simult ...... fies hematopoietic regulators.

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J.DEVCEL.2011.04.008

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Developmental Cell

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Ariel Forrai

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Derek L Stemple

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Marloes R Tijssen

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Rebecca L Hannah

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S Helen Oram

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Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

Model-based analysis of ChIP-Seq (MACS)

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

A HaemAtlas: characterizing gene expression in differentiated human blood cells

JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update

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Willem H Ouwehand

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Anthony R Green

Dana Bellissimo

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