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Specificity of short interfering RNA determined through gene expression signatures.

Specificity of short interfering RNA determined through gene expression signatures.

http://www.wikidata.org/entity/Q35142877

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Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells Thyroid transcription factor in differentiating type II cells: regulation, isoforms, and target genes Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo A computational study of off-target effects of RNA interference The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.DEQOR: a web-based tool for the design and quality control of siRNAs RNA interference: biology, mechanism, and applications A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target Functional complementation of RNA interference mutants in trypanosomes Towards in vivo application of RNA interference - new toys, old problems Sequence-specific inhibition of small RNA function Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivo A rapid and sensitive assay for quantification of siRNA efficiency and specificity Quantum dots to monitor RNAi delivery and improve gene silencing Tolerated wobble mutations in siRNAs decrease specificity, but can enhance activity in vivo.In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5.Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells Nanotoxicity: a key obstacle to clinical translation of siRNA-based nanomedicine Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference Zscan4: a novel gene expressed exclusively in late 2-cell embryos and embryonic stem cells Applying gene silencing technology to contraception Targeted gene silencing to induce permanent sterility Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells.siRNA-mediated gene silencing: a global genome view.Oligonucleotide-based knockdown technologies: antisense versus RNA interference.Post-transcriptional gene silencing induced by short interfering RNAs in cultured transgenic plant cells.Specific and nontoxic silencing in mammalian cells with expressed long dsRNAs.Designing siRNA that distinguish between genes that differ by a single nucleotide Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: quantitative analysis of uptake and biological effect.An accurate and interpretable model for siRNA efficacy prediction.Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling.A structural analysis of in vitro catalytic activities of hammerhead ribozymes.Off-target effects of siRNA specific for GFP

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P2860

Specificity of short interfering RNA determined through gene expression signatures.

http://www.wikidata.org/entity/Q35142877

description

2003 nî lūn-bûn

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2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2003 թվականի մայիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Specificity of short interfering RNA determined through gene expression signatures.

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Specificity of short interfering RNA determined through gene expression signatures.

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type

label

Specificity of short interfering RNA determined through gene expression signatures.

@ast

Specificity of short interfering RNA determined through gene expression signatures.

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prefLabel

Specificity of short interfering RNA determined through gene expression signatures.

@ast

Specificity of short interfering RNA determined through gene expression signatures.

@en

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PNAS.1131959100

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Specificity of short interfering RNA determined through gene expression signatures.

@en

P2093

Aparna Sarthy

http://www.w3.org/2001/XMLSchema#string

Dimitri Semizarov

http://www.w3.org/2001/XMLSchema#string

Donald N Halbert

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Leigh Frost

http://www.w3.org/2001/XMLSchema#string

Paul Kroeger

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P2860

Gene expression profiling predicts clinical outcome of breast cancer

RNA interference is mediated by 21- and 22-nucleotide RNAs

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

RefSeq and LocusLink: NCBI gene-centered resources

siRNAs can function as miRNAs

Multiclass cancer diagnosis using tumor gene expression signatures

Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs

Molecular classification of cutaneous malignant melanoma by gene expression profiling

Rb function in cell-cycle regulation and apoptosis.

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10.1073/PNAS.1131959100

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11

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100

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Stephen W. Fesik

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2003-05-13T00:00:00Z

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10759486

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164449

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