Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype. - Wikidata - wikimedia - TriplyDB

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.

http://www.wikidata.org/entity/Q35149689

about

Regulation of TAZ in cancer Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor.Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.Hypoxia-inducible factors in cancer stem cells and inflammation.HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells.HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells.The hypoxic tumor microenvironment: A driving force for breast cancer progression.Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells Navigating the bone marrow niche: translational insights and cancer-driven dysfunction.HMG-CoAR expression in male breast cancer: relationship with hormone receptors, Hippo transducers and survival outcomes.The Hippo transducers TAZ/YAP and their target CTGF in male breast cancer.Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.The Hippo signaling pathway provides novel anti-cancer drug targets.The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells.Mechanisms of marrow adiposity and its implications for skeletal health.Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1α and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro.SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.Addressing intra-tumoral heterogeneity and therapy resistance.Hypoxia-inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype.Maintenance of redox homeostasis by hypoxia-inducible factors.Association between AXL, Hippo Transducers, and Survival Outcomes in Male Breast Cancer.Downregulation of miR-874-3p promotes chemotherapeutic resistance in colorectal cancer via inactivation of the Hippo signaling pathway.The history and regulatory mechanism of the Hippo pathway.In Vitro Assays of Breast Cancer Stem Cells.TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism.Alternative Splicing in the Hippo Pathway-Implications for Disease and Potential Therapeutic Targets.The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.Expression of phosphorylated Hippo pathway kinases (MST1/2 and LATS1/2) in HER2-positive and triple-negative breast cancer patients treated with neoadjuvant therapy.

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P2860

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.

http://www.wikidata.org/entity/Q35149689

description

2014 nî lūn-bûn

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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Hypoxia-inducible factor 1 med ...... st cancer stem cell phenotype.

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Hypoxia-inducible factor 1 med ...... st cancer stem cell phenotype.

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Hypoxia-inducible factor 1 med ...... st cancer stem cell phenotype.

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Hypoxia-inducible factor 1 med ...... st cancer stem cell phenotype.

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Daniele M Gilkes

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Debangshu Samanta

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Haiquan Lu

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Hongxia Hu

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Houjie Liang

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John W Bullen

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Lisha Xiang

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Naoharu Takano

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Weibo Luo

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P2860

Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment.

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

The hippo signaling pathway in development and cancer

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

Comprehensive molecular portraits of human breast tumours

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.

Role of hypoxia-inducible factors in breast cancer metastasis

Hypoxia-inducible factors in physiology and medicine

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12509-12527

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scholarly article

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10.18632/ONCOTARGET.2997

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24

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5

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Gregg L. Semenza

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2014-12-01T00:00:00Z

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270909575

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