Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis - Wikidata - wikimedia - TriplyDB

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis

http://www.wikidata.org/entity/Q35158836

about

Animal models of systemic sclerosis: their utility and limitations.Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species.Methyl-β-cyclodextrin up-regulates collagen I expression in chronologically-aged skin via its anti-caveolin-1 activity Caveolin-1, cellular senescence and age-related diseases.Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells.Metabolic fingerprints of human primary endothelial and fibroblast cells Interstitial lung diseases-can pathologists arrive at an etiology-based diagnosis? A critical update.Autophagy: controlling cell fate in rheumatic diseases.Caveolin-1 in the Pathogenesis of Diabetic Nephropathy: Potential Therapeutic Target?Autophagy and mesenchymal cell fibrogenesis.Caveolin-1 deficiency protects against mesangial matrix expansion in a mouse model of type 1 diabetic nephropathy.Autophagy is a key feature in the pathogenesis of systemic sclerosis.Development and progression of immobilization-induced skin fibrosis through overexpression of transforming growth factor-ß1 and hypoxic conditions in a rat knee joint contracture model.Metabolomic profile of systemic sclerosis patients.

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P2860

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis

http://www.wikidata.org/entity/Q35158836

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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Scleroderma-like properties of ...... ibrosis and systemic sclerosis

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Alex Molchansky

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David P Beason

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George Purkins

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Louis J Soslowsky

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Remedios Castello-Cros

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Renato V Iozzo

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P2860

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice

Myofibroblasts and hyalinized collagen as markers of skin disease in systemic sclerosis.

Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis.

Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast

Collagenase in scleroderma.

Caveolae: from cell biology to animal physiology.

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10.4161/CC.10.13.16227

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Michael P. Lisanti

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Federica Sotgia

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