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Coordinated regulation of polycomb group complexes through microRNAs in cancer.

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

http://www.wikidata.org/entity/Q35167450

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Novel RNA markers in prostate cancer: functional considerations and clinical translation The emergence of lncRNAs in cancer biology Maternal exposure to diethylstilbestrol during pregnancy and increased breast cancer risk in daughters EZH2 in Bladder Cancer, a Promising Therapeutic Target Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis.A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.Influence of oncogenic transcription factors on chromatin conformation and implications in prostate cancer.The central role of EED in the orchestration of polycomb group complexes.MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells Superior efficacy of a combined epigenetic therapy against human mantle cell lymphoma cells.Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance.microRNA-141 regulates BMI1 expression and induces senescence in human diploid fibroblasts.Regulation and Role of EZH2 in Cancer EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis miRNAs and cancer: an epigenetics view.The miR-124-prolyl hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression.Molecular pathways and targets in prostate cancer Epigenetic alteration and microRNA dysregulation in cancer EZH2: biology, disease, and structure-based drug discovery Aldosterone regulates microRNAs in the cortical collecting duct to alter sodium transport.Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc.JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines.EZH2 promotes angiogenesis through inhibition of miR-1/Endothelin-1 axis in nasopharyngeal carcinoma.Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells.Polycomb genes, miRNA, and their deregulation in B-cell malignancies MicroRNA-214 suppresses oncogenesis and exerts impact on prognosis by targeting PDRG1 in bladder cancer.RNA interference targeting enhancer of polycomb1 exerts anti-tumor effects in lung cancer.RASAL2 activates RAC1 to promote triple-negative breast cancer progression Structural basis for VEGF-C binding to neuropilin-2 and sequestration by a soluble splice form.Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2 NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells.Role of bacterial infection in the epigenetic regulation of Wnt antagonist WIF1 by PRC2 protein EZH2.MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2 Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines.Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells.Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells.

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P2860

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

http://www.wikidata.org/entity/Q35167450

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

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Coordinated regulation of polycomb group complexes through microRNAs in cancer.

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type

label

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

@ast

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

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prefLabel

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

@ast

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

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Coordinated regulation of polycomb group complexes through microRNAs in cancer

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Arul M Chinnaiyan

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Arun Dahiya

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Christopher A Maher

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J Chad Brenner

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Jindan Yu

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Jung H Kim

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Lei Wang

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Mithil Pandhi

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Qi Cao

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Ram-Shankar Mani

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P2860

The Polycomb group protein EZH2 directly controls DNA methylation

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB

Role of histone H2A ubiquitination in Polycomb silencing

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

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John R. Prensner

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Saravana M Dhanasekaran

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