about
Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivoTargeting NF-kappaB in hematologic malignanciesPleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19bSmall-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myelomaPU.1 induces apoptosis in myeloma cells through direct transactivation of TRAILPI3K/p110{delta} is a novel therapeutic target in multiple myeloma.The effects of selective cytokine inhibitory drugs (CC-10004 and CC-1088) on VEGF and IL-6 expression and apoptosis in myeloma and endothelial cell co-cultures.Perifosine , an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity.JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells.Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo.Zoledronic acid exerts its antitumor effect in multiple myeloma interfering with the bone marrow microenvironment.Current therapeutic uses of lenalidomide in multiple myeloma.Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain.A review of lenalidomide in combination with dexamethasone for the treatment of multiple myeloma.Integrated cellular bone homeostasis model for denosumab pharmacodynamics in multiple myeloma patients.Ricolinostat (ACY-1215) induced inhibition of aggresome formation accelerates carfilzomib-induced multiple myeloma cell death.Nanoparticle delivery systems, general approaches, and their implementation in multiple myeloma.The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells.The effects of thalidomide on chemotactic migration of multiple myeloma cell lines.Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo.Toll-like receptors mediate proliferation and survival of multiple myeloma cells.Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cellsMolecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Novel therapeutic approaches for multiple myeloma.
@ast
Novel therapeutic approaches for multiple myeloma.
@en
type
label
Novel therapeutic approaches for multiple myeloma.
@ast
Novel therapeutic approaches for multiple myeloma.
@en
prefLabel
Novel therapeutic approaches for multiple myeloma.
@ast
Novel therapeutic approaches for multiple myeloma.
@en
P2860
P1476
Novel therapeutic approaches for multiple myeloma.
@en
P2093
Teru Hideshima
P2860
P304
P356
10.1034/J.1600-065X.2003.00053.X
P577
2003-08-01T00:00:00Z