Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases
about
Proof-of-concept, randomized, controlled clinical trial of Bacillus-Calmette-Guerin for treatment of long-term type 1 diabetesImmunoproteasomes: structure, function, and antigen presentationA case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat.Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓCorneal wound healing is compromised by immunoproteasome deficiency.Enhanced inflammatory potential of CD4+ T-cells that lack proteasome immunosubunit expression, in a T-cell transfer-based colitis model.Immunoproteasome deficiency protects in the retina after optic nerve crush.Proteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitisCollective Genetic Interaction Effects and the Role of Antigen-Presenting Cells in Autoimmune Diseases.Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.Current understanding on the role of standard and immunoproteasomes in inflammatory/immunological pathways of multiple sclerosis.Vitiligo blood transcriptomics provides new insights into disease mechanisms and identifies potential novel therapeutic targets.Self-antigen presentation by dendritic cells in autoimmunity.Proteasome inhibitors as experimental therapeutics of autoimmune diseases.Dysfunction in protein clearance by the proteasome: impact on autoinflammatory diseases.CD8(+) T cells of Listeria monocytogenes-infected mice recognize both linear and spliced proteasome products.Low Neurotoxicity of ONX-0914 Supports the Idea of Specific Immunoproteasome Inhibition as a Side-Effect-Limiting, Therapeutic Strategy.mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress.The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T cell repertoire.Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome.
P2860
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P2860
Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@ast
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@en
type
label
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@ast
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@en
prefLabel
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@ast
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@en
P2093
P2860
P356
P1476
Proteasome immunosubunits prot ...... l-mediated autoimmune diseases
@en
P2093
Alice J A M Sijts
Andrea Gröne
Benedicte A Lie
Cornelis P J Bekker
Dietmar M W Zaiss
P2860
P304
P356
10.4049/JIMMUNOL.1101003
P407
P577
2011-07-29T00:00:00Z