Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes - Wikidata - wikimedia - TriplyDB

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

http://www.wikidata.org/entity/Q34234705

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Proof-of-concept, randomized, controlled clinical trial of Bacillus-Calmette-Guerin for treatment of long-term type 1 diabetes Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes Systemic perturbations of key metabolites in diabetic rats during the evolution of diabetes studied by urine metabonomics Serum Cytokines as Biomarkers in Islet Cell Transplantation for Type 1 Diabetes Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation.Ex vivo TCR-induced leukocyte gene expression of inflammatory mediators is increased in type 1 diabetic patients but not in overweight children Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin.Immunotherapy of type 1 diabetes: where are we and where should we be going?Incidental CD8 T cell reactivity against caspase-cleaved apoptotic self-antigens from ubiquitously expressed proteins in islets from prediabetic human leucocyte antigen-A2 transgenic non-obese diabetic mice.Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells.Killer artificial antigen-presenting cells: the synthetic embodiment of a 'guided missile'.Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin.T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner Immune profiling by multiple gene expression analysis in patients at-risk and with type 1 diabetes Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes.Tissue-specific methylation of human insulin gene and PCR assay for monitoring beta cell death.Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.Single insulin-specific CD8+ T cells show characteristic gene expression profiles in human type 1 diabetes.Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.The Development and Application of HLA Tetramers in the Detection, Characterization and Therapy of Type 1 Diabetes Mellitus.Antigen targets of type 1 diabetes autoimmunity Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.Diabetes tolerogenic vaccines targeting antigen-specific inflammation Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.Etiopathogenesis of insulin autoimmunity.

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Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

http://www.wikidata.org/entity/Q34234705

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@ast

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@en

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@nl

type

label

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@ast

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@en

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@nl

prefLabel

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@ast

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@en

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@nl

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PNAS.0508621102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

@en

P2093

Bart Keymeulen

http://www.w3.org/2001/XMLSchema#string

Bart O Roep

http://www.w3.org/2001/XMLSchema#string

Cees A M Bergen

http://www.w3.org/2001/XMLSchema#string

Danny Pipeleers

http://www.w3.org/2001/XMLSchema#string

Ferry Ossendorp

http://www.w3.org/2001/XMLSchema#string

Gabrielle G M Pinkse

http://www.w3.org/2001/XMLSchema#string

Jan W Drijfhout

http://www.w3.org/2001/XMLSchema#string

Michel G D Kester

http://www.w3.org/2001/XMLSchema#string

Odette H M Tysma

http://www.w3.org/2001/XMLSchema#string

P2860

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

Phenotypic analysis of antigen-specific T lymphocytes

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry.

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.

Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.

Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

Endoplasmic reticulum stress and the development of diabetes: a review.

The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure.

P304

18425-18430

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scholarly article

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10.1073/PNAS.0508621102

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P407

P433

51

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102

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Peter van Veelen

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2005-12-09T00:00:00Z

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7429699

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16339897

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P921

type-1 diabetes

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1317949

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