PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1. - Wikidata - wikimedia - TriplyDB

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

http://www.wikidata.org/entity/Q35186284

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Enhancing tumor-targeting monoclonal antibodies therapy by PARP inhibitors Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation Role of AKT signaling in DNA repair and clinical response to cancer therapy.MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1.Metformin impairs the growth of liver kinase B1-intact cervical cancer cells.Erythropoietin-driven signalling and cell migration mediated by polyADP-ribosylation.miR-451 regulates FoxO3 nuclear accumulation through Ywhaz in human colorectal cancer Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications Beyond DNA Repair: Additional Functions of PARP-1 in Cancer.

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P2860

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

http://www.wikidata.org/entity/Q35186284

description

2011 nî lūn-bûn

@nan

2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

@ast

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

@en

type

label

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

@ast

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

@en

prefLabel

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

@ast

PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.

@en

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J.BBRC.2011.07.107

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Biochemical and Biophysical Research Communications

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PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1

@en

P2093

Ben C Davis

http://www.w3.org/2001/XMLSchema#string

Huibo Wang

http://www.w3.org/2001/XMLSchema#string

Jiyong Liang

http://www.w3.org/2001/XMLSchema#string

Sai-Juan Chen

http://www.w3.org/2001/XMLSchema#string

Shuai Wang

http://www.w3.org/2001/XMLSchema#string

Zhi-Xiang Xu

http://www.w3.org/2001/XMLSchema#string

P2860

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis

Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

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379-384

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2

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phosphorylation

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