Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms

Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms

Item
http://www.wikidata.org/entity/Q24658292
Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicityPHLPP1 splice variants differentially regulate AKT and PKCα signaling in hippocampal neurons: characterization of PHLPP proteins in the adult hippocampusTwo hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Protein kinase signaling networks in cancer.The emerging role of the phosphatidylinositol 3-kinase/ akt/mammalian target of rapamycin signaling network in cancer stem cell biology.Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells.Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway.
P2860

Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms

Item
http://www.wikidata.org/entity/Q24658292
description
2009 nî lūn-bûn
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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@ast
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@en
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@nl
type
label
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@ast
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@en
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@nl
prefLabel
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@ast
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@en
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Depletion of Pleckstrin homolo ...... hosphorylation of Akt isoforms
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932