Cytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding.
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A multifunctional mesothelin antibody-tagged microparticle targets human mesotheliomasEffect of antigen shedding on targeted delivery of immunotoxins in solid tumors from a mathematical modelDiscovery of mesothelin and exploiting it as a target for immunotherapy.Mesothelin Immunotherapy for Cancer: Ready for Prime Time?Megakaryocytic potentiating factor and mature mesothelin stimulate the growth of a lung cancer cell line in the peritoneal cavity of mice.Combination treatments with the PKC inhibitor, enzastaurin, enhance the cytotoxicity of the anti-mesothelin immunotoxin, SS1P.Antigen shedding may improve efficiencies for delivery of antibody-based anticancer agents in solid tumorsReduced Shedding of Surface Mesothelin Improves Efficacy of Mesothelin-Targeting Recombinant ImmunotoxinsModulating mesothelin shedding to improve therapy.Peritoneal dissemination of ovarian cancer: role of MUC16-mesothelin interaction and implications for treatment.Antibody-Drug Conjugates as Cancer Therapeutics: Past, Present, and Future.A new anti-mesothelin antibody targets selectively the membrane-associated form.Overexpression of periostin and distinct mesothelin forms predict malignant progression in a rat cholangiocarcinoma model.Purification of clinical-grade disulfide stabilized antibody fragment variable--Pseudomonas exotoxin conjugate (dsFv-PE38) expressed in Escherichia coli.The Impact of Mesothelin in the Ovarian Cancer Tumor Microenvironment
P2860
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P2860
Cytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@ast
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@en
type
label
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@ast
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@en
prefLabel
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@ast
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@en
P2093
P2860
P1433
P1476
Cytotoxic activity of immunoto ...... dependent mesothelin shedding.
@en
P2093
Ira Pastan
Jingli Zhang
Oleg Chertov
Raffit Hassan
Yujian Zhang
P2860
P304
P356
10.1158/0008-5472.CAN-11-0466
P407
P577
2011-07-20T00:00:00Z