Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin.
about
Genetic characterization of the Drosophila birt-hogg-dubé syndrome genemTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4EGOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancerSignaling by target of rapamycin proteins in cell growth controlInsulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signalingElucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell developmentmTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cellsPhosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinasesRole of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacksThe mTOR signalling pathway in human cancerAn emerging role for TOR signaling in mammalian tissue and stem cell physiologyExpression of Drosophila FOXO regulates growth and can phenocopy starvationUsing Drosophila to discover mechanisms underlying type 2 diabetesThe developmental control of size in insectsNutrient-sensing mechanisms across evolutionNutrient regulation of the mTOR complex 1 signaling pathwayThe Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body SizeCyclin G Functions as a Positive Regulator of Growth and Metabolism in DrosophilaFatty acid synthase cooperates with glyoxalase 1 to protect against sugar toxicityTIF-IA-dependent regulation of ribosome synthesis in drosophila muscle is required to maintain systemic insulin signaling and larval growthThe Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycinNotch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineageSMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planariansLifespan extension in a semelparous chordate occurs via developmental growth arrest just prior to meiotic entryEnhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression.Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene.Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway.Modeling dietary influences on offspring metabolic programming in Drosophila melanogasterRegulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation siteRapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TORThe protein kinase Tor1 regulates adhesin gene expression in Candida albicansRapamycin response in tumorigenic and non-tumorigenic hepatic cell linesFRAP/mTOR is required for proliferation and patterning during embryonic development in the mouseRegulation of TORC1 by Rag GTPases in nutrient responseRegulation of the mTOR complex 1 pathway by nutrients, growth factors, and stressMammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4EAkt regulates growth by directly phosphorylating Tsc2
P2860
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P2860
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Genetic and biochemical charac ...... og of the target of rapamycin.
@ast
Genetic and biochemical charac ...... og of the target of rapamycin.
@en
type
label
Genetic and biochemical charac ...... og of the target of rapamycin.
@ast
Genetic and biochemical charac ...... og of the target of rapamycin.
@en
prefLabel
Genetic and biochemical charac ...... og of the target of rapamycin.
@ast
Genetic and biochemical charac ...... og of the target of rapamycin.
@en
P2093
P2860
P356
P1433
P1476
Genetic and biochemical charac ...... og of the target of rapamycin.
@en
P2093
P2860
P304
P356
10.1101/GAD.845700
P577
2000-11-01T00:00:00Z