Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis

Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis

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http://www.wikidata.org/entity/Q35214727
Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress.Cyclin-dependent kinase inhibitor dinaciclib potently synergizes with cisplatin in preclinical models of ovarian cancer.Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivoRapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105.Critical reanalysis of the methods that discriminate the activity of CDK2 from CDK1Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells.Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737.Toward a cure for chronic lymphocytic leukemia: an attack on multiple frontsThe putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA.Manipulating the apoptotic pathway: potential therapeutics for cancer patients.Microtubule destabilising agents: far more than just antimitotic anticancer drugs.JNK and NFκB dependence of apoptosis induced by vinblastine in human acute promyelocytic leukaemia cells.
P2860

Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis

Item
http://www.wikidata.org/entity/Q35214727
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2011 nî lūn-bûn
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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
@wuu
name
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@ast
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@en
type
label
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@ast
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@en
prefLabel
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@ast
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Vinblastine sensitizes leukemi ...... le phase-independent apoptosis
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932