Functional analysis of DNA gyrase mutant enzymes carrying mutations at position 88 in the A subunit found in clinical strains of Mycobacterium tuberculosis resistant to fluoroquinolones.
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Structural Insights into the Quinolone Resistance Mechanism of Mycobacterium tuberculosis DNA GyraseAggressive regimens for multidrug-resistant tuberculosis decrease all-cause mortalityResistance of M. leprae to quinolones: a question of relativity?Detection by GenoType MTBDRsl test of complex mechanisms of resistance to second-line drugs and ethambutol in multidrug-resistant Mycobacterium tuberculosis complex isolates.Pseudo-outbreak of pre-extensively drug-resistant (Pre-XDR) tuberculosis in Kinshasa: collateral damage caused by false detection of fluoroquinolone resistance by GenoType MTBDRsl.Molecular diagnosis of fluoroquinolone resistance in Mycobacterium tuberculosis.DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis.Clinical application of whole-genome sequencing to inform treatment for multidrug-resistant tuberculosis cases.A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system.Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis.Mutations in gyrA and gyrB among Fluoroquinolone- and Multidrug-Resistant Mycobacterium tuberculosis Isolates.Mutagenesis in the alpha3alpha4 GyrA helix and in the Toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones.Comprehensive treatment of extensively drug-resistant tuberculosis.Beijing genotype of Mycobacterium tuberculosis is significantly associated with high-level fluoroquinolone resistance in Vietnam.Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.Prevalence and molecular characterization of fluoroquinolone-resistant Mycobacterium tuberculosis isolates in China.Nanocarrier-based interventions for the management of MDR/XDR-TB.Double mutation in DNA gyrase confers moxifloxacin resistance and decreased fitness of Mycobacterium smegmatis.GenoType MTBDRsl for molecular detection of second-line-drug and ethambutol resistance in Mycobacterium tuberculosis strains and clinical samples.A novel resistance mutation in eccC5 of the ESX-5 secretion system confers ofloxacin resistance in Mycobacterium tuberculosis.Are all the DNA gyrase mutations found in Mycobacterium leprae clinical strains involved in resistance to fluoroquinolones?Characteristic resistance mechanism of Mycobacterium tuberculosis to DC-159a, a new respiratory quinolone.Cluster-based molecular docking study for in silico identification of novel 6-fluoroquinolones as potential inhibitors against Mycobacterium tuberculosis.
P2860
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P2860
Functional analysis of DNA gyrase mutant enzymes carrying mutations at position 88 in the A subunit found in clinical strains of Mycobacterium tuberculosis resistant to fluoroquinolones.
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2006 nî lūn-bûn
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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@ast
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@en
type
label
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@ast
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@en
prefLabel
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@ast
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@en
P2093
P2860
P356
P1476
Functional analysis of DNA gyr ...... resistant to fluoroquinolones.
@en
P2093
Alexandra Aubry
Chantal Truffot-Pernot
Claudine Mayer
Elisabeth Bouvet
Emmanuelle Cambau
Juliette Camuset
Stéphanie Matrat
Vincent Jarlier
P2860
P304
P356
10.1128/AAC.00944-06
P407
P577
2006-10-02T00:00:00Z