Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation.
about
Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tauDown-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory.Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficitsApparent behavioral benefits of tau overexpression in P301L tau transgenic miceFrontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus.Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of ratsRole of p73 in Alzheimer disease: lack of association in mouse models or in human cohortsKnock-out and transgenic mouse models of tauopathies.Immunotherapeutic approaches for Alzheimer's disease in transgenic mouse models.Vaccination as a therapeutic approach to Alzheimer's disease.Murine models of Alzheimer's disease and their use in developing immunotherapies.Modelling early responses to neurodegenerative mutations in mice.Review: tauopathy in the retina and optic nerve: does it shadow pathological changes in the brain?Tau and neurodegenerative disorders.The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition.A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy.Longitudinal evaluation of Tau-P301L transgenic mice reveals no cognitive impairments at 17 months of age.Tau-Induced Pathology in Epilepsy and Dementia: Notions from Patients and Animal Models.
P2860
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P2860
Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@ast
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@en
type
label
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@ast
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@en
prefLabel
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@ast
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@en
P2093
P2860
P1476
Cortical neuronal and glial pa ...... nce, and phenotypic variation.
@en
P2093
Amanda Hanna
Amie L Phinney
Atsushi Sasaki
Catherine Bergeron
Christopher Janus
David Westaway
Erwan Paitel
Etsuro Matsubara
George A Carlson
P2860
P304
P356
10.2353/AJPATH.2006.051250
P407
P577
2006-10-01T00:00:00Z