Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines.
about
Glycosylation of glycolipids in cancer: basis for development of novel therapeutic approachesAutologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients.Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptorsMetabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside-protein complex.Robust immune responses elicited by a fully synthetic three-component vaccine.Synthesis and evaluation of monophosphoryl lipid A derivatives as fully synthetic self-adjuvanting glycoconjugate cancer vaccine carriersMetabolism of diazirine-modified N-acetylmannosamine analogues to photo-cross-linking sialosides.Carbohydrate engineered cells for regenerative medicine.Total synthesis of trifluorobutyryl-modified, globally protected sialyl Lewis x by a convergent [2+2] approachModified GM3 gangliosides produced by metabolic oligosaccharide engineeringSynthesis and Evaluation of Protein Conjugates of GM3 Derivatives Carrying Modified Sialic Acids as Highly Immunogenic Cancer Vaccine CandidatesIdentification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells.Carbohydrate-monophosphoryl lipid a conjugates are fully synthetic self-adjuvanting cancer vaccines eliciting robust immune responses in the mouseA novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells.Recent Development in Carbohydrate Based Anti-cancer Vaccines.Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell.A novel synthetic bipartite carrier protein for developing glycotope-based vaccines.A Fully Synthetic Self-Adjuvanting Globo H-Based Vaccine Elicited Strong T Cell-Mediated Antitumor Immunity.Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona FormationFully Synthetic Self-Adjuvanting α-2,9-Oligosialic Acid Based Conjugate Vaccines against Group C Meningitis.Improving the antigenicity of sTn antigen by modification of its sialic acid residue for development of glycoconjugate cancer vaccinesSynthetic and immunological studies of 5'-N-phenylacetyl sTn to develop carbohydrate-based cancer vaccines and to explore the impacts of linkage between carbohydrate antigens and carrier proteinsParallel chemoenzymatic synthesis of sialosides containing a C5-diversified sialic acidCombining synthetic carbohydrate vaccines with cancer cell glycoengineering for effective cancer immunotherapy.Carbohydrate vaccines: developing sweet solutions to sticky situations?Recent development in carbohydrate-based cancer vaccines.Eliciting carbohydrate-specific immune response against sialosides: success and challenges.Recent advances in developing synthetic carbohydrate-based vaccines for cancer immunotherapies.Carbohydrate-based cancer vaccines: target cancer with sugar bullets.Discovery and design of carbohydrate-based therapeutics.The sweet side of tumor immunotherapy.Chemoenzymatic Syntheses of Sialylated Oligosaccharides Containing C5-Modified Neuraminic Acids for Dual Inhibition of Hemagglutinins and Neuraminidases.Cloning and characterization of a viral α2-3-sialyltransferase (vST3Gal-I) for the synthesis of sialyl Lewisx.Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications.Enhanced interferon-gamma secretion and antitumor activity of T-lymphocytes activated by dendritic cells loaded with glycoengineered myeloma antigens.A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model.Metabolic Glycoengineering with N-Acyl Side Chain Modified Mannosamines.N-Propionyl polysialic acid precursor enhances the susceptibility of multiple myeloma to antitumor effect of anti-NprPSA monoclonal antibody.Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example.Progress in the synthesis and biological evaluation of lipid A and its derivatives.
P2860
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P2860
Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@ast
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@en
type
label
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@ast
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@en
prefLabel
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@ast
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@en
P2093
P2860
P356
P1476
Synthesis and immunological pr ...... s therapeutic cancer vaccines.
@en
P2093
Clifford Harding
Nancy Nagy
Peter Chefalo
Yanbin Pan
Zhongwu Guo
P2860
P304
P356
10.1021/JM0494422
P407
P577
2005-02-01T00:00:00Z