Robust immune responses elicited by a fully synthetic three-component vaccine.
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Vaccine adjuvants as potential cancer immunotherapeuticsSynthetic self-adjuvanting glycopeptide cancer vaccinesStrategy for Designing a Synthetic Tumor Vaccine: Multi-Component, Multivalency and Antigen ModificationGlycotherapy: new advances inspire a reemergence of glycans in medicineA nonself sugar mimic of the HIV glycan shield shows enhanced antigenicitySynthetic Nanoparticles for Vaccines and ImmunotherapyToll Like Receptors Signaling Pathways as a Target for Therapeutic InterventionsResolving conflicting data on expression of the Tn antigen and implications for clinical trials with cancer vaccinesFrom synthesis to biologics: preclinical data on a chemistry derived anticancer vaccineDevelopment, characterization, and immunotherapeutic use of peptide mimics of the Thomsen-Friedenreich carbohydrate antigen.Identification of novel synthetic toll-like receptor 2 agonists by high throughput screening.Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptorsLinear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunityChemical synthesis and proinflammatory responses of monophosphoryl lipid A adjuvant candidates.Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc.Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist.Antibody recognition of fluorinated MUC1 glycopeptide antigens.Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model.Synthesis of homogeneous MUC1 oligomers via a bi-directional ligation strategy.Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4'-deoxy-4'-fluoro-Thomsen-Friedenreich epitope.Cancer vaccines and carbohydrate epitopes.Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine.Perorally active nanomicellar formulation of quercetin in the treatment of lung cancerLinear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide.Recent Development in Carbohydrate Based Anti-cancer Vaccines.Intact reducing glycan promotes the specific immune response to lacto-N-neotetraose-BSA neoglycoconjugates.A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity.Design and synthesis of multifunctional gold nanoparticles bearing tumor-associated glycopeptide antigens as potential cancer vaccinesPreparation and immunogenicity of gold glyco-nanoparticles as antipneumococcal vaccine model.Effects of hapten density on the induced antibody repertoireA mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design.Scalable synthesis of Fmoc-protected GalNAc-threonine amino acid and T(N) antigen via nickel catalysis.A Fully Synthetic Self-Adjuvanting Globo H-Based Vaccine Elicited Strong T Cell-Mediated Antitumor Immunity.Clustered carbohydrates in synthetic vaccines.Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.Glycan antagonists and inhibitors: a fount for drug discovery.Aberrant O-glycosylation and anti-glycan antibodies in an autoimmune disease IgA nephropathy and breast adenocarcinoma.Carbohydrates and T cells: a sweet twosome.Biologics through chemistry: total synthesis of a proposed dual-acting vaccine targeting ovarian cancer by orchestration of oligosaccharide and polypeptide domains.A vision for vaccines built from fully synthetic tumor-associated antigens: from the laboratory to the clinic
P2860
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P2860
Robust immune responses elicited by a fully synthetic three-component vaccine.
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Robust immune responses elicited by a fully synthetic three-component vaccine.
@ast
Robust immune responses elicited by a fully synthetic three-component vaccine.
@en
type
label
Robust immune responses elicited by a fully synthetic three-component vaccine.
@ast
Robust immune responses elicited by a fully synthetic three-component vaccine.
@en
prefLabel
Robust immune responses elicited by a fully synthetic three-component vaccine.
@ast
Robust immune responses elicited by a fully synthetic three-component vaccine.
@en
P2093
P2860
P356
P1476
Robust immune responses elicited by a fully synthetic three-component vaccine.
@en
P2093
Jidnyasa Gaekwad
Sampat Ingale
Therese Buskas
P2860
P2888
P304
P356
10.1038/NCHEMBIO.2007.25
P577
2007-09-02T00:00:00Z