Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex.
about
Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cellsVisualization of a polytopic membrane protein during SecY-mediated membrane insertionMgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes.Co- and Post-Translational Protein Folding in the ERSignal peptide-binding drug as a selective inhibitor of co-translational protein translocationKinetic analysis of ribosome-bound fluorescent proteins reveals an early, stable, cotranslational folding intermediate.A flip turn for membrane protein insertion.Type II transmembrane domain hydrophobicity dictates the cotranslational dependence for inversion.Cotranslational folding inhibits translocation from within the ribosome-Sec61 translocon complex.Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the transloconTransmembrane segments of nascent polytopic membrane proteins control cytosol/ER targeting during membrane integrationCotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events.Determining the N-terminal orientations of recombinant transmembrane proteins in the Escherichia coli plasma membrane.Direct simulation of early-stage Sec-facilitated protein translocationRegulation of multispanning membrane protein topology via post-translational annealing.Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integrationThe Ribosome-Sec61 Translocon Complex Forms a Cytosolically Restricted Environment for Early Polytopic Membrane Protein Folding.Intra-plastid protein trafficking: how plant cells adapted prokaryotic mechanisms to the eukaryotic condition.Long-timescale dynamics and regulation of Sec-facilitated protein translocation.Exploring the nature of the translocon-assisted protein insertion.Understanding integration of α-helical membrane proteins: the next stepsSec62 protein mediates membrane insertion and orientation of moderately hydrophobic signal anchor proteins in the endoplasmic reticulum (ER)Evolutionary well-conserved region in the signal peptide of parathyroid hormone-related protein is critical for its dual localization through the regulation of ER translocation.Regional discrimination and propagation of local rearrangements along the ribosomal exit tunnel.Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex.An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate.Adaptation of low-resolution methods for the study of yeast microsomal polytopic membrane proteins: a methodological review.The safety dance: biophysics of membrane protein folding and misfolding in a cellular contextRefined topology model of the STT3/Stt3 protein subunit of the oligosaccharyltransferase complex.Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis.Positional editing of transmembrane domains during ion channel assembly.Membrane protein TM segments are retained at the translocon during integration until the nascent chain cues FRET-detected release into bulk lipid.Co-translational processing of glycoprotein 3 from equine arteritis virus: N-glycosylation adjacent to the signal peptide prevents cleavage.Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling.An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases.Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents.Plastid ribosome pausing is induced by multiple features and is linked to protein complex assembly.Two-step insertion at the SecY translocon.
P2860
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P2860
Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@ast
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@en
type
label
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@ast
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@en
prefLabel
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@ast
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@en
P2093
P2860
P1433
P1476
Stepwise insertion and inversi ...... some-Sec61 translocon complex.
@en
P2093
Arthur E Johnson
Brian Conti
Prasanna K Devaraneni
William R Skach
Yoshihiro Matsumura
Zhongying Yang
P2860
P304
P356
10.1016/J.CELL.2011.06.004
P407
P577
2011-07-01T00:00:00Z