Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity. - Wikidata - wikimedia - TriplyDB

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.

http://www.wikidata.org/entity/Q35237500

about

Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types Herpes simplex virus and varicella zoster virus, the house guests who never leave Severe infectious diseases of childhood as monogenic inborn errors of immunity Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems Primary immunodeficiencies of pattern recognition receptors Novel approaches and challenges to treatment of central nervous system viral infections Toll-like receptors: key players in antiviral immunity STAT2 deficiency and susceptibility to viral illness in humans Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients Proteomics in immunity and herpes simplex encephalitis.Prophylactic and therapeutic modulation of innate and adaptive immunity against mucosal infection of herpes simplex virus Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB Update on herpes virus infections of the nervous system.TLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk.Interplay between Kaposi's sarcoma-associated herpesvirus and the innate immune system.Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives.A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4 Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.Plasmacytoid dendritic cells contribute to systemic but not local antiviral responses to HSV infections.Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice.Expression of nucleic acid-sensing Toll-like receptors predicts HPV16 clearance associated with an E6-directed cell-mediated response Evasion of early antiviral responses by herpes simplex viruses.Poly(I:C) induces antiviral immune responses in Japanese flounder (Paralichthys olivaceus) that require TLR3 and MDA5 and is negatively regulated by Myd88.Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency Inborn errors of anti-viral interferon immunity in humans.Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16 Role of specific innate immune responses in herpes simplex virus infection of the central nervous system TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice Functional IRF3 deficiency in a patient with herpes simplex encephalitis.Translational research in infectious disease: current paradigms and challenges ahead.The Roles and Perspectives of Toll-Like Receptors and CD4(+) Helper T Cell Subsets in Acute Viral Encephalitis.Sex differences in the response to viral infections: TLR8 and TLR9 ligand stimulation induce higher IL10 production in males.Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood Herpesvirus infections of the central nervous system in immunocompromised patients Toll-like receptor signaling in primary immune deficiencies.Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus.Type I interferons: diversity of sources, production pathways and effects on immune responses.

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P2860

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.

http://www.wikidata.org/entity/Q35237500

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Herpes simplex virus encephali ...... undant in protective immunity.

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Herpes simplex virus encephali ...... undant in protective immunity.

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Herpes simplex virus encephali ...... undant in protective immunity.

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Herpes simplex virus encephali ...... undant in protective immunity.

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Herpes simplex virus encephali ...... undant in protective immunity.

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Herpes simplex virus encephali ...... undant in protective immunity.

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Journal of Experimental Medicine

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Herpes simplex virus encephali ...... undant in protective immunity.

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P2093

Annabelle Cardon

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Elodie Pauwels

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Esperanza Anguiano

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Flore Rozenberg

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Joana Azevedo

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Magali Audry

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Marc Tardieu

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Paul Bastard Philippe

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Pierre Lebon

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Valérie Doireau

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P2860

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses

Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

Pyogenic bacterial infections in humans with MyD88 deficiency

Role of macrophages in natural resistance to virus infections

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Pyogenic bacterial infections in humans with IRAK-4 deficiency

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

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2083-2098

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10.1084/JEM.20101568

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10

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208

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Jean-Laurent Casanova

Shen-Ying Zhang

Emmanuelle Jouanguy

Sabine Plancoulaine

Capucine Picard

Rebeca Perez de Diego

Frederic Geissmann

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2011-09-12T00:00:00Z

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51631782

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21911422

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Toll-like receptor

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3182056

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