Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
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Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological DisordersInduced Pluripotency and Gene Editing in Disease Modelling: Perspectives and ChallengesSevere infectious diseases of childhood as monogenic inborn errors of immunityModeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived SystemsNovel approaches and challenges to treatment of central nervous system viral infectionsDeciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous SystemProgramming and Reprogramming Cellular Age in the Era of Induced PluripotencyInnate immune detection of microbial nucleic acids.Herpes simplex encephalitis as a complication of neurosurgical procedures: report of 3 cases and review of the literatureAstrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder ResearchHuman IFNAR2 deficiency: Lessons for antiviral immunityAn image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouseHuman stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypesCasein kinase II controls TBK1/IRF3 activation in IFN response against viral infection.Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors.Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory NeuronsDissecting mammalian immunity through mutation.Intrinsic innate immunity fails to control herpes simplex virus and vesicular stomatitis virus replication in sensory neurons and fibroblasts.A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency.Coxsackievirus B4 myocarditis and meningoencephalitis in newborn twins.Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies.TLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk.Concise review: modeling central nervous system diseases using induced pluripotent stem cellsGenome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody responseEstablishment of HSV1 latency in immunodeficient mice facilitates efficient in vivo reactivation.Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kindEvasion of early antiviral responses by herpes simplex viruses.Both MicroRNA-155 and Virus-Encoded MiR-155 Ortholog Regulate TLR3 Expression.Neuronal Interferon Signaling Is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis.Normocellular CSF in herpes simplex encephalitis.Functional IRF3 deficiency in a patient with herpes simplex encephalitis.The Regulation of Immunological Processes by Peripheral Neurons in Homeostasis and DiseaseLatency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear EnvironmentTLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking.Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and ImmunopathologyToll-like receptor signaling in primary immune deficiencies.REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.Profile of Jean-Laurent Casanova.UNC93B1 mediates differential trafficking of endosomal TLRs.
P2860
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P2860
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@ast
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@en
type
label
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@ast
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@en
altLabel
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells
@en
prefLabel
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@ast
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@en
P2093
P2860
P50
P356
P1433
P1476
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
@en
P2093
Avinash Abhyankar
Fabien G Lafaille
Gustavo Mostoslavsky
Itai M Pessach
Luigi D Notarangelo
Marc Tardieu
Saleh Al-Muhsen
Shui-Wang Ying
Sotirios Keros
P2860
P2888
P304
P356
10.1038/NATURE11583
P407
P50
P577
2012-10-28T00:00:00Z
P5875
P6179
1031249211