APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway
about
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesisAdiponectin signaling and function in insulin target tissues5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complicationsThe orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPKOverexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivityAdiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial DysfunctionZinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytesActivation of AMPK Stimulates Neurotensin Secretion in Neuroendocrine CellsAPPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.Repression of class I transcription by cadmium is mediated by the protein phosphatase 2A.Liver Kinase B1 complex acts as a novel modifier of myofilament function and localizes to the Z-disk in cardiac myocytesMetabolic function of the CTRP family of hormones.microRNA-25 targets PKCζ and protects osteoblastic cells from dexamethasone via activating AMPK signalingThe role of adiponectin signaling in metabolic syndrome and cancer.A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway.Can Adiponectin Help us to Target Diastolic Dysfunction?TWEAK prevents TNF-α-induced insulin resistance through PP2A activation in human adipocytes.The adiponectin-SIRT1-AMPK pathway in alcoholic fatty liver disease in the rat.Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation.Targeting PP2A activates AMPK signaling to inhibit colorectal cancer cells.APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction.Adiponectin inhibits inflammatory cytokines production by Beclin-1 phosphorylation and Bcl-2 mRNA destabilization: Role for autophagy induction.Adiponectin mediated APPL1-AMPK signaling induces cell migration, MMP activation, and collagen remodeling in cardiac fibroblasts.Metformin and berberine, two versatile drugs in treatment of common metabolic diseases.
P2860
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P2860
APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@ast
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@en
type
label
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@ast
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@en
prefLabel
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@ast
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@en
P2093
P2860
P356
P1476
APPL1 mediates adiponectin-ind ...... PP2A-PKCzeta signaling pathway
@en
P2093
Changhua Wang
Jiyoon Ryu
Lijun Zhou
Lily Q Dong
Nicolas Musi
Ning Zhang
Sathyaseelan S Deepa
Xuming Mao
P2860
P304
P356
10.1210/ME.2011-0082
P577
2011-08-11T00:00:00Z