LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
about
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasmActivation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRADHeat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stabilityHonokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesisIonizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophyIdentification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndromeIntegrin-binding protein nischarin interacts with tumor suppressor liver kinase B1 (LKB1) to regulate cell migration of breast epithelial cells.Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia.Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function.LKB1, a protein kinase regulating cell proliferation and polarity.LKB1 (XEEK1) regulates Wnt signalling in vertebrate development.LKB1, the multitasking tumour suppressor kinaseFunctional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.STRAD in Peutz-Jeghers syndrome and sporadic cancers.APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathwayCancer risks in LKB1 germline mutation carriers.Inference of modules associated to eQTLs.Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell lineAdiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways.Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunctionMolecular mechanisms of tumor suppression by LKB1.The LKB1 complex-AMPK pathway: the tree that hides the forestThe protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signalingNegative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinomaRestoration of silenced Peutz-Jeghers syndrome gene, LKB1, induces apoptosis in pancreatic carcinoma cells.Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.Inactivation of the LKB1-AMPK signaling pathway does not contribute to salivary gland tumor development - a short report.LKB1 gene alterations in surgically resectable adenocarcinoma of the lung.The altered activity of P53 signaling pathway by STK11 gene mutations and its cancer phenotype in Peutz-Jeghers syndromeHamartomatous polyposis syndromes
P2860
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P2860
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
description
2001 nî lūn-bûn
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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
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2001年學術文章
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name
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@ast
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en-gb
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@nl
type
label
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@ast
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en-gb
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@nl
prefLabel
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@ast
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en-gb
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@nl
P2093
P356
P1476
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1
@en
P2093
A Ashworth
C Niederlander
S I Rayter
P304
P356
10.1093/HMG/10.25.2869
P407
P577
2001-12-01T00:00:00Z