about
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)Ubc13: the Lys63 ubiquitin chain building machineThe roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunityThe role of targeted protein degradation in early neural developmentIL-17 family: cytokines, receptors and signalingThe IL-23-IL-17 immune axis: from mechanisms to therapeutic testingThe IL-17 pathway as a major therapeutic target in autoimmune diseasesIL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tailNegative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammationAncient origin of animal U-box ubiquitin ligases.IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expressionTPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling.Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosaThe differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signalingInterleukin-17 Indirectly Promotes M2 Macrophage Differentiation through Stimulation of COX-2/PGE2 Pathway in the Cancer Cells.A custom 148 gene-based resequencing chip and the SNP explorer software: new tools to study antibody deficiency.SEF/IL-17R (SEFIR) is not enough: an extended SEFIR domain is required for il-17RA-mediated signal transduction.Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.Ubiquitin makes its mark on immune regulation.AZD5363 Inhibits Inflammatory Synergy between Interleukin-17 and Insulin/Insulin-Like Growth Factor 1IL-17-induced NF-kappaB activation via CIKS/Act1: physiologic significance and signaling mechanismsThe anaphase-promoting complex protein 5 (AnapC5) associates with A20 and inhibits IL-17-mediated signal transduction.Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera.Interleukin-17A promotes MUC5AC expression and goblet cell hyperplasia in nasal polyps via the Act1-mediated pathway.TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses.Recent advances in the IL-17 cytokine family.IL-17 and insulin/IGF1 enhance adhesion of prostate cancer cells to vascular endothelial cells through CD44-VCAM-1 interactionEnhanced meta-analysis and replication studies identify five new psoriasis susceptibility lociA CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.CIKS/Act1-mediated signaling by IL-17 cytokines in context: implications for how a CIKS gene variant may predispose to psoriasis.Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages.A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1.TRAF6-dependent Act1 phosphorylation by the IκB kinase-related kinases suppresses interleukin-17-induced NF-κB activationCharacterization of Lamprey IL-17 Family Members and Their Receptors.CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy.Cutting edge: TNF receptor-associated factor 4 restricts IL-17-mediated pathology and signaling processes.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
@ast
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
@en
type
label
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
@ast
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
@en
prefLabel
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
@ast
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
@en
P2093
P2860
P1433
P1476
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling
@en
P2093
Natalia V Giltiay
Shadi Swaidani
Xiaoxia Li
Youcun Qian
P2860
P356
10.1126/SCISIGNAL.2000382
P577
2009-10-13T00:00:00Z