Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies
about
Sirtuins and nonalcoholic fatty liver diseaseRole of the Substrate Specificity-Defining Residues of Human SIRT5 in Modulating the Structural Stability and Inhibitory Features of the Enzyme.Physiological and pathophysiological roles of NAMPT and NAD metabolism.Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells.An improved fluorogenic assay for SIRT1, SIRT2, and SIRT3.Correction: Mechanism of Inhibition of the Human Sirtuin Enzyme SIRT3 by Nicotinamide: Computational and Experimental Studies.Correction: Correction: Mechanism of Inhibition of the Human Sirtuin Enzyme SIRT3 by Nicotinamide: Computational and Experimental Studies.The Role of Sirtuins in Antioxidant and Redox Signaling.Characterization of CobB kinetics and inhibition by nicotinamide.Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6.The impact of cellular metabolism on chromatin dynamics and epigenetics.Metabolic intermediates - Cellular messengers talking to chromatin modifiers.Development of Activity-Based Chemical Probes for Human Sirtuins.Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults.Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2.Biophysical characterization of hit compounds for mechanism-based enzyme activation.
P2860
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P2860
Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies
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2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Mechanism of inhibition of the ...... ional and experimental studies
@ast
Mechanism of inhibition of the ...... ional and experimental studies
@en
type
label
Mechanism of inhibition of the ...... ional and experimental studies
@ast
Mechanism of inhibition of the ...... ional and experimental studies
@en
prefLabel
Mechanism of inhibition of the ...... ional and experimental studies
@ast
Mechanism of inhibition of the ...... ional and experimental studies
@en
P2093
P2860
P1433
P1476
Mechanism of inhibition of the ...... ional and experimental studies
@en
P2093
Eric Knoll
Raj Chakrabarti
Xiangying Guan
P2860
P304
P356
10.1371/JOURNAL.PONE.0107729
P407
P50
P577
2014-09-15T00:00:00Z