Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.

Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.

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http://www.wikidata.org/entity/Q35266484
Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrheaPLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cellsLysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling.Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity.Rapamycin Inhibition of mTOR Reduces Levels of the Na+/H+ Exchanger 3 in Intestines of Mice and Humans, Leading to Diarrhea.NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangersPDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs.Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes.Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells.Calmodulin-dependent binding to the NHE1 cytosolic tail mediates activation of the Na+/H+ exchanger by Ca2+ and endothelin.
P2860

Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.

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http://www.wikidata.org/entity/Q35266484
description
2011 nî lūn-bûn
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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@ast
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@en
type
label
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@ast
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@en
prefLabel
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@ast
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Elevated calcium acutely regul ...... m kidney (OK) cell microvilli.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932