Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).
about
Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodiesIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysChimeric plantibody passively protects mice against aerosolized ricin challenge.Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB).Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin's binding subunitMechanistic insights into the neutralization of cytotoxic abrin by the monoclonal antibody D6F10.Characterization and epitope mapping of the polyclonal antibody repertoire elicited by ricin holotoxin-based vaccinationImmunity to ricin: fundamental insights into toxin-antibody interactions.Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit.A novel recombinant vaccine protecting mice against abrin intoxication.Isolation of Anti-Ricin Protective Antibodies Exhibiting High Affinity from Immunized Non-Human Primates.Monoclonal antibodies and toxins--a perspective on function and isotype.Mechanisms of Ricin Toxin Neutralization Revealed through Engineered Homodimeric and Heterodimeric Camelid Antibodies.Targeting ricin to the ribosome.Comparative efficacy of two leading candidate ricin toxin a subunit vaccines in mice.A recombinant chimeric protein containing B chains of ricin and abrin is an effective vaccine candidate.Immunomodulatory activity of recombinant Ricin toxin binding Subunit B (RTB).Neutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro.Structural insights into the neutralization mechanism of monoclonal antibody 6C2 against ricin.Neutralizing activity and protective immunity to ricin toxin conferred by B subunit (RTB)-specific Fab fragmentsStepwise engineering of heterodimeric single domain camelid VHH antibodies that passively protect mice from ricin toxin.Active immunity induced by passive IgG post-exposure protection against ricin.Antibody-mediated inhibition of ricin toxin retrograde transport.Progress and challenges associated with the development of ricin toxin subunit vaccines.Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.Milk inhibits the biological activity of ricin.High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin.Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects.RTB lectin-mediated delivery of lysosomal α-l-iduronidase mitigates disease manifestations systemically including the central nervous system.Production, Characterisation and Testing of an Ovine Antitoxin against Ricin; Efficacy, Potency and Mechanisms of Action.A Supercluster of Neutralizing Epitopes at the Interface of Ricin's Enzymatic (RTA) and Binding (RTB) Subunits.Antibody Interactions withRicinus communisAgglutinins Studied by Biolayer Interferometry
P2860
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P2860
Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Protective immunity to ricin t ...... toxin's binding subunit (RTB).
@ast
Protective immunity to ricin t ...... toxin's binding subunit (RTB).
@en
type
label
Protective immunity to ricin t ...... toxin's binding subunit (RTB).
@ast
Protective immunity to ricin t ...... toxin's binding subunit (RTB).
@en
prefLabel
Protective immunity to ricin t ...... toxin's binding subunit (RTB).
@ast
Protective immunity to ricin t ...... toxin's binding subunit (RTB).
@en
P2860
P1433
P1476
Protective immunity to ricin t ...... toxin's binding subunit (RTB)
@en
P2093
Anastasiya Yermakova
P2860
P304
P356
10.1016/J.VACCINE.2011.08.075
P407
P577
2011-08-26T00:00:00Z