E2F1-dependent oncogenic addiction of melanoma cells to MDM2. - Wikidata - wikimedia - TriplyDB

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

http://www.wikidata.org/entity/Q35353609

about

E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα.Loss of keratinocytic RXRα combined with activated CDK4 or oncogenic NRAS generates UVB-induced melanomas via loss of p53 and PTEN in the tumor microenvironment.p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis.The role of miR-18b in MDM2-p53 pathway signaling and melanoma progression HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.Transcription addiction: can we garner the Yin and Yang functions of E2F1 for cancer therapy?BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.Effect of downregulation of ZEB1 on vimentin expression, tumour migration and tumourigenicity of melanoma B16F10 cells and CSCs.E2F1 inhibition mediates cell death of metastatic melanoma.

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E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

http://www.wikidata.org/entity/Q35353609

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

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E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

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type

label

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

@ast

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

@en

prefLabel

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

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E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

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E2F1-dependent oncogenic addiction of melanoma cells to MDM2

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A Checinska

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M B Riblett

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M Verhaegen

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A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

Interaction between the retinoblastoma protein and the oncoprotein MDM2

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

Cancer statistics, 2010

The genetics of the p53 pathway, apoptosis and cancer therapy.

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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828-841

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10.1038/ONC.2011.277

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María S Soengas

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